Literature DB >> 1667578

ERKs, extracellular signal-regulated MAP-2 kinases.

M H Cobb1, D J Robbins, T G Boulton.   

Abstract

A family of protein kinases, known alternatively as microtubule-associated protein-2/myelin basic protein kinases or extracellular signal-regulated kinases, is activated by numerous hormones, growth factors and other extracellular stimuli. At least two members of this family function as intermediate kinases in protein phosphorylation cascades. Their mechanisms of activation may involve autophosphorylation, which occurs on both threonine and tyrosine residues.

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Year:  1991        PMID: 1667578     DOI: 10.1016/0955-0674(91)90124-h

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN: 0955-0674            Impact factor:   8.382


  39 in total

1.  Involvement of the MAP kinase cascade in resetting of the mammalian circadian clock.

Authors:  M Akashi; E Nishida
Journal:  Genes Dev       Date:  2000-03-15       Impact factor: 11.361

2.  Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase.

Authors:  K Diener; X S Wang; C Chen; C F Meyer; G Keesler; M Zukowski; T H Tan; Z Yao
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-02       Impact factor: 11.205

3.  Overexpression of LIM kinase 1 renders resistance to apoptosis in PC12 cells by inhibition of caspase activation.

Authors:  E Yang; H Kim; J Lee; J S Shin; H Yoon; S J Kim; I H Choi
Journal:  Cell Mol Neurobiol       Date:  2004-04       Impact factor: 5.046

4.  Quantitative analysis of ERK2 interactions with substrate proteins: roles for kinase docking domains and activity in determining binding affinity.

Authors:  Kimberly A Burkhard; Fengming Chen; Paul Shapiro
Journal:  J Biol Chem       Date:  2010-11-22       Impact factor: 5.157

5.  alpha(1)-Adrenergic receptor subtype function in fetal and adult cerebral arteries.

Authors:  Ravi Goyal; Ashwani Mittal; Nina Chu; Lubo Zhang; Lawrence D Longo
Journal:  Am J Physiol Heart Circ Physiol       Date:  2010-03-26       Impact factor: 4.733

6.  Activation of raf-1, MEK, and MAP kinase in prolactin responsive mammary cells.

Authors:  R Das; B K Vonderhaar
Journal:  Breast Cancer Res Treat       Date:  1996       Impact factor: 4.872

7.  Adapter protein SH2-B beta undergoes nucleocytoplasmic shuttling: implications for nerve growth factor induction of neuronal differentiation.

Authors:  Linyi Chen; Christin Carter-Su
Journal:  Mol Cell Biol       Date:  2004-05       Impact factor: 4.272

8.  Sphingolipid metabolites differentially regulate extracellular signal-regulated kinase and stress-activated protein kinase cascades.

Authors:  E Coroneos; Y Wang; J R Panuska; D J Templeton; M Kester
Journal:  Biochem J       Date:  1996-05-15       Impact factor: 3.857

9.  Multiple signaling pathways in bovine chromaffin cells regulate tyrosine hydroxylase phosphorylation at Ser19, Ser31, and Ser40.

Authors:  J W Haycock
Journal:  Neurochem Res       Date:  1993-01       Impact factor: 3.996

10.  Human mitogen-activated protein kinase kinase kinase mediates the stress-induced activation of mitogen-activated protein kinase cascades.

Authors:  P Y Chan-Hui; R Weaver
Journal:  Biochem J       Date:  1998-12-15       Impact factor: 3.857

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