Literature DB >> 1667533

Intercellular communication in cultured rabbit gastric epithelial cells.

F Ueda1, T Kyoi, K Mimura, K Kimura, M Yamamoto.   

Abstract

The effects of drugs related to cyclic AMP and a tumor promoter, phorbol ester, on intercellular communications via gap junctions were investigated by the Lucifer Yellow-transfer method in cultured rabbit gastric epithelial cells. Cells were in contact with each drug for 4 hr before the microinjection of the dye into a cell. Dye transfer capacity was significantly increased by dibutyryl cyclic AMP (10(-3) M), theophylline (10(-3) M), 3-isobutyl-1-methylxanthine (10(-4) M), forskolin (10(-6) M) and irsogladine (10(-4) M); and it was inhibited by 12-O-tetradecanoyl-phorbol-13-acetate (100 ng/ml). These results suggest that the intercellular communication between cultured rabbit gastric epithelial cells is upregulated by cyclic AMP.

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Year:  1991        PMID： 1667533     DOI： 10.1254/jjp.57.321

Source DB:  PubMed          Journal:  Jpn J Pharmacol        ISSN： 0021-5198


  8 in total

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2.  Irsogladine maleate regulates gap junctional intercellular communication-dependent epithelial barrier in human nasal epithelial cells.

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Journal:  J Membr Biol       Date:  2015-02-05       Impact factor: 1.843

3.  Suppressing effects of 6-(2,5-dichlorophenyl)-2,4-diamino-1,3,5-triazine and related synthetic compounds on azoxymethane-induced aberrant crypt foci in rat colon.

Authors:  Y Hirose; T Tanaka; H Makita; M Yang; K Satoh; A Hara; M Maeda; H B Toriyama; H Mori; H Tsuda
Journal:  Jpn J Cancer Res       Date:  1996-06

4.  Triazine derivatives inhibit rat hepatocarcinogenesis but do not enhance gap junctional intercellular communication.

Authors:  T Hori; M Asamoto; V Krutovskikh; Y Iwahori; M Maeda; H Toriyama-Baba; N Takasuka; H Tsuda
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Review 5.  Roles of connexins and pannexins in digestive homeostasis.

Authors:  Michaël Maes; Bruno Cogliati; Sara Crespo Yanguas; Joost Willebrords; Mathieu Vinken
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6.  Preventive effect of irsogladine or omeprazole on non-steroidal anti-inflammatory drug-induced esophagitis, peptic ulcers, and small intestinal lesions in humans, a prospective randomized controlled study.

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Journal:  BMC Gastroenterol       Date:  2013-05-14       Impact factor: 3.067

7.  Suppressive effect of irsogladine maleate on diethylnitrosamine-initiated and phenobarbital-promoted hepatocarcinogenesis in male F344 rats.

Authors:  S Sugie; K Okamoto; F Ueda; T Watanabe; T Tanaka; H Mori
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Review 8.  Regulation of defensive function on gingival epithelial cells can prevent periodontal disease.

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  8 in total

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