Literature DB >> 16674060

A facile, general synthesis of 3,4-difluoro-6-substituted-2-pyrones.

Yi Wang1, Donald J Burton.   

Abstract

Reaction of (2E)-2,3-difluoro-3-iodoacrylic acid with a variety of terminal acetylenes under cocatalysis of PdCl2(PPh3)2 and CuI gave difluorinated 2-pyrones as the sole product in good yields.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16674060     DOI： 10.1021/jo060362a

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  7 in total

1.  Recent advances in the synthetic and mechanistic aspects of the ruthenium-catalyzed carbon-heteroatom bond forming reactions of alkenes and alkynes.

Authors:  Chae S Yi
Journal:  J Organomet Chem       Date:  2011-01-01       Impact factor: 2.369

2.  Catalysis by orotidine 5'-monophosphate decarboxylase: effect of 5-fluoro and 4'-substituents on the decarboxylation of two-part substrates.

Authors:  Bogdana Goryanova; Krisztina Spong; Tina L Amyes; John P Richard
Journal:  Biochemistry       Date:  2013-01-11       Impact factor: 3.162

3.  Scope and Mechanistic Investigations on the Solvent-Controlled Regio- and Stereoselective Formation of Enol Esters from the Ruthenium-Catalyzed Coupling Reaction of Terminal Alkynes and Carboxylic Acids.

Authors:  Chae S Yi; Ruili Gao
Journal:  Organometallics       Date:  2009-10-30       Impact factor: 3.876

Review 4.  Recent advances in the synthesis of 2-pyrones.

Authors:  Jong Seok Lee
Journal:  Mar Drugs       Date:  2015-03-23       Impact factor: 5.118

5.  Base Mediated Tandem Vinylogous Addition and Cyclization of γ-Phosphonyl/Sulfonyl Crotonates and Ynones: Synthesis of Functionalized 2-Pyrones.

Authors:  Matam Parameshwar; Manda Rajesh; Sridhar Balasubramanian; Maddi Sridhar Reddy
Journal:  ACS Omega       Date:  2019-10-30

6.  Solving the enigma of weak fluorine contacts in the solid state: a periodic DFT study of fluorinated organic crystals.

Authors:  Elena O Levina; Ivan Y Chernyshov; Alexander P Voronin; Leonid N Alekseiko; Adam I Stash; Mikhail V Vener
Journal:  RSC Adv       Date:  2019-04-23       Impact factor: 4.036

7.  Alkynyl triazenes enable divergent syntheses of 2-pyrones.

Authors:  Jin-Fay Tan; Carl Thomas Bormann; Kay Severin; Nicolai Cramer
Journal:  Chem Sci       Date:  2021-06-04       Impact factor: 9.825
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.