| Literature DB >> 16671802 |
Pauline C Stanislawski1, Anthony C Willis, Martin G Banwell.
Abstract
[reaction: see text] Treatment of the anion derived from the ring-fused gem-dichlorocyclopropane 4c with silver tetrafluoroborate afforded the spirocyclic compound 17 in 74% yield. Product 17 was readily converted, over three steps, into the beta-iodoethyl derivative 20 and treatment of this latter compound with n-Bu(3)SnH then afforded, in 93% yield and via a radical addition/elimination sequence, compound 2 incorporating the ABCD framework of the aromatic erythrina alkaloids.Entities:
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Year: 2006 PMID: 16671802 DOI: 10.1021/ol060642c
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005