Literature DB >> 16671801

Cross metathesis with strained exocyclic enones: synthesis of 3-alkylideneoxetan-2-ones from 3-methyleneoxetan-2-ones.

Ravinder Raju1, Amy R Howell.   

Abstract

[reaction: see text] 3-Alkylideneoxetan-2-ones have been prepared in good to excellent yields with high Z-selectivity by olefin cross metathesis with 3-methyleneoxetan-2-ones in the presence of second generation metathesis catalysts 1 or 2.

Entities:  

Year:  2006        PMID： 16671801     DOI： 10.1021/ol060624v

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Rh-Catalyzed Conjugate Addition of Aryl and Alkenyl Boronic Acids to α-Methylene-β-lactones: Stereoselective Synthesis of trans-3,4-Disubstituted β-Lactones.

Authors:  Christian A Malapit; Irungu K Luvaga; Donald R Caldwell; Nicholas K Schipper; Amy R Howell
Journal:  Org Lett       Date:  2017-08-15       Impact factor: 6.005

2.  Pd-Catalyzed Acyl C-O Bond Activation for Selective Ring-Opening of α-Methylene-β-lactones with Amines.

Authors:  Christian A Malapit; Donald R Caldwell; Nicole Sassu; Samuel Milbin; Amy R Howell
Journal:  Org Lett       Date:  2017-04-04       Impact factor: 6.005

3.  Combining cross-metathesis and activity-based protein profiling: new β-lactone motifs for targeting serine hydrolases.

Authors:  Kaddy Camara; Siddhesh S Kamat; Celina C Lasota; Benjamin F Cravatt; Amy R Howell
Journal:  Bioorg Med Chem Lett       Date:  2015-01-15       Impact factor: 2.823

4.  Ligand-Controlled Palladium-Catalyzed Carbonylation of Alkynols: Highly Selective Synthesis of α-Methylene-β-Lactones.

Authors:  Yao Ge; Fei Ye; Jiawang Liu; Ji Yang; Anke Spannenberg; Haijun Jiao; Ralf Jackstell; Matthias Beller
Journal:  Angew Chem Int Ed Engl       Date:  2020-09-17       Impact factor: 15.336
  4 in total

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