Literature DB >> 16669917

Oligozoospermia: recent prognosis and the outcome of 73 pregnancies in oligozoospermic couples.

J A van Zyl1, R Menkveld.   

Abstract

The minimum value for each of the five main semen parameters, below which conception rarely occurred or did not occur at all, was calculated in a group of 1884 couples complaining of primary and secondary infertility: 304 conceptions including first as well as consecutive conceptions, occurred. The parameters evaluated were (minimum value calculated in this study between brackets) volume (1.0 ml), sperm count ml(-1) (2.0 million), total sperm count (4.0 million), motility (10%), forward progression (2.0 MacLeod units: scale 1-4) and normal sperm morphology (3%). The pregnancy rate in the group of 308 oligozoospermic men and the minimum value of semen parameters were the cornerstones in determining the prognosis for oligozoospermic patients. A sperm count of >2.0 million ml(-1) was considered relatively adequate for eventual conception judged by the 68 of 308 (22.1%) pregnancies that occurred among oligozoospermic men in this study, provided that the other five semen parameters showed values above the minimum value. In cases where the average sperm count was <2 million ml(-1), the chances for conception became rare, viz five of 308 (1.6%). The total number of pregnancies in the group classified as oligozoospermic was 73 (23.7%). With these pregnancies there was no increase in the rate of foetal wastage and congenital abnormalities. Abortion occurred in 15.09% and ectopic pregnancy in 0.9% among first and consecutive pregnancies. One infant among the 56% boys and 44% girls was born with congenital abnormalities. Most of these infants had a normal birth mass of >2500 g.

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Year:  2006        PMID: 16669917     DOI: 10.1111/j.1439-0272.2006.00720.x

Source DB:  PubMed          Journal:  Andrologia        ISSN: 0303-4569            Impact factor:   2.775


  5 in total

1.  Clinical significance of the low normal sperm morphology value as proposed in the fifth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen.

Authors:  Roelof Menkveld
Journal:  Asian J Androl       Date:  2010-01       Impact factor: 3.285

2.  SpermCheck Fertility, an immunodiagnostic home test that detects normozoospermia and severe oligozoospermia.

Authors:  M A Coppola; K L Klotz; K-a Kim; H Y Cho; J Kang; J Shetty; S S Howards; C J Flickinger; J C Herr
Journal:  Hum Reprod       Date:  2010-02-05       Impact factor: 6.918

3.  Clinical and consumer trial performance of a sensitive immunodiagnostic home test that qualitatively detects low concentrations of sperm following vasectomy.

Authors:  Kenneth L Klotz; Michael A Coppola; Michel Labrecque; Victor M Brugh; Kim Ramsey; Kyung-ah Kim; Mark R Conaway; Stuart S Howards; Charles J Flickinger; John C Herr
Journal:  J Urol       Date:  2008-10-19       Impact factor: 7.450

4.  Decreased fecundity and sperm DNA methylation patterns.

Authors:  Timothy G Jenkins; Kenneth I Aston; Tyson D Meyer; James M Hotaling; Monis B Shamsi; Erica B Johnstone; Kyley J Cox; Joseph B Stanford; Christina A Porucznik; Douglas T Carrell
Journal:  Fertil Steril       Date:  2015-10-09       Impact factor: 7.329

5.  Perceived negative consequences of donor gametes from male and female members of infertile couples.

Authors:  Michael L Eisenberg; James F Smith; Susan G Millstein; Thomas J Walsh; Benjamin N Breyer; Patricia P Katz
Journal:  Fertil Steril       Date:  2009-06-12       Impact factor: 7.329

  5 in total

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