Literature DB >> 16669142

[Epidemiology of asthma and allergies. The prevalence of allergies increases worldwide, and asthma has reached his highest-ever prevalence in Europe: why?].

Michel Aubier1, Françoise Neukirch, Isabella Annesi-Maesano.   

Abstract

Up to 10% of adults and 35% of children worldwide suffer from asthma. The incidence of asthma is also higher in children than in adults, possibly owing to a "cohort" effect. Recent population-based studies show that the increase in the prevalence of asthma noted worldwide in the past 30 years has started to subside in industrialised countries. This phenomenon has been accompanied by a parallel increase in the use of asthma medications. Possible explanations for this increase include the "hygiene hypothesis", which implicates diminished exposure to microbial pathogens but was recently challenged by new biological and immunological findings. Asthma might result from the interactions between individual and environmental factors (diet, air pollution, etc.), but further investigations are needed to understand the precise pathophysiological mechanisms of asthma.

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Year:  2005        PMID: 16669142

Source DB:  PubMed          Journal:  Bull Acad Natl Med        ISSN: 0001-4079            Impact factor:   0.144


  3 in total

Review 1.  Developments in the field of allergy in 2009 through the eyes of Clinical and Experimental Allergy.

Authors:  H W Chu; C M Lloyd; W Karmaus; P Maestrelli; P Mason; G Salcedo; J Thaikoottathil; A J Wardlaw
Journal:  Clin Exp Allergy       Date:  2010-11       Impact factor: 5.018

2.  Nitration of the egg-allergen ovalbumin enhances protein allergenicity but reduces the risk for oral sensitization in a murine model of food allergy.

Authors:  Eva Untersmayr; Susanne C Diesner; Gertie Janneke Oostingh; Kathrin Selzle; Tobias Pfaller; Cornelia Schultz; Yingyi Zhang; Durga Krishnamurthy; Philipp Starkl; Regina Knittelfelder; Elisabeth Förster-Waldl; Arnold Pollak; Otto Scheiner; Ulrich Pöschl; Erika Jensen-Jarolim; Albert Duschl
Journal:  PLoS One       Date:  2010-12-02       Impact factor: 3.240

3.  Modeling the impact of genetic screening technologies on healthcare: theoretical model for asthma in children.

Authors:  Emma Gutiérrez de Mesa; Ignacio Hidalgo; Panayotis Christidis; Juan Carlos Ciscar; Eva Vegas; Dolores Ibarreta
Journal:  Mol Diagn Ther       Date:  2007       Impact factor: 4.074

  3 in total

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