Literature DB >> 1665883

New insights into mechanisms of oxyradical and neutrophil mediated lung injury.

P A Ward1, M S Mulligan.   

Abstract

Acute lung injury in rats developing after systemic complement activation or deposition of IgG immune complexes is complement-dependent and oxygen radical-mediated. Recent findings have shown that a soluble complement receptor (sCR1) is capable of attenuating injury. Additional studies have also demonstrated requirements for the cytokines, TNF alpha, and for L-arginine derived products in lung injury that follows deposition of IgG immune complexes.

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Year:  1991        PMID： 1665883     DOI： 10.1007/bf01645148

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN： 0023-2173


  10 in total

1.  Tissue injury caused by deposition of immune complexes is L-arginine dependent.

Authors:  M S Mulligan; J M Hevel; M A Marletta; P A Ward
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

2.  Nitric oxide: a cytotoxic activated macrophage effector molecule.

Authors:  J B Hibbs; R R Taintor; Z Vavrin; E M Rachlin
Journal:  Biochem Biophys Res Commun       Date:  1988-11-30       Impact factor: 3.575

3.  Role of oxygen metabolites in immune complex injury of lung.

Authors:  K J Johnson; P A Ward
Journal:  J Immunol       Date:  1981-06       Impact factor: 5.422

4.  Tumor necrosis factor participates in the pathogenesis of acute immune complex alveolitis in the rat.

Authors:  J S Warren; K R Yabroff; D G Remick; S L Kunkel; S W Chensue; R G Kunkel; K J Johnson; P A Ward
Journal:  J Clin Invest       Date:  1989-12       Impact factor: 14.808

5.  Superoxide responses of immune complex-stimulated rat alveolar macrophages. Intracellular calcium and priming.

Authors:  B E Hagenlocker; B A Walker; P A Ward
Journal:  J Immunol       Date:  1990-05-15       Impact factor: 5.422

6.  Intravascular activation of complement and acute lung injury. Dependency on neutrophils and toxic oxygen metabolites.

Authors:  G O Till; K J Johnson; R Kunkel; P A Ward
Journal:  J Clin Invest       Date:  1982-05       Impact factor: 14.808

7.  Acute immunologic pulmonary alveolitis.

Authors:  K J Johnson; P A Ward
Journal:  J Clin Invest       Date:  1974-08       Impact factor: 14.808

8.  Intrapulmonary interleukin 1 mediates acute immune complex alveolitis in the rat.

Authors:  J S Warren
Journal:  Biochem Biophys Res Commun       Date:  1991-03-15       Impact factor: 3.575

9.  Recombinant soluble human complement receptor type 1 inhibits inflammation in the reversed passive arthus reaction in rats.

Authors:  C G Yeh; H C Marsh; G R Carson; L Berman; M F Concino; S M Scesney; R E Kuestner; R Skibbens; K A Donahue; S H Ip
Journal:  J Immunol       Date:  1991-01-01       Impact factor: 5.422

10.  Soluble human complement receptor type 1: in vivo inhibitor of complement suppressing post-ischemic myocardial inflammation and necrosis.

Authors:  H F Weisman; T Bartow; M K Leppo; H C Marsh; G R Carson; M F Concino; M P Boyle; K H Roux; M L Weisfeldt; D T Fearon
Journal:  Science       Date:  1990-07-13       Impact factor: 47.728
  10 in total
  2 in total

Review 1.  Concepts of oxidative stress and antioxidant defense in Crohn's disease.

Authors:  Mohammed A Alzoghaibi
Journal:  World J Gastroenterol       Date:  2013-10-21       Impact factor: 5.742

2.  Effects of mineral fibers on the expression of genes whose product may play a role in fiber pathogenesis.

Authors:  T Tsuda; Y Morimoto; H Yamato; H Nakamura; H Hori; N Nagata; M Kido; T Higashi; I Tanaka
Journal:  Environ Health Perspect       Date:  1997-09       Impact factor: 9.031
  2 in total

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