Literature DB >> 1665776

Determination of estrogenic/antiestrogenic potential of antifertility substances using rat uterine peroxidase assay.

R K Johri1, G S Pahwa, S C Sharma, U Zutshi.   

Abstract

The effect of three compounds (clomiphene citrate, centchroman, embelin) and plant-derived methanolic extracts (Abutilon indicum and Butea monosperma) was studied on uterotropic and uterine peroxidase activities in ovariectomized rats. It was observed that these two parameters were highly correlated in response to treatment with these test materials and also to estradiol. It was suggested that the uterine peroxidase assay could be utilized as a biochemical parameter in the screening of new antifertility agents for their estrogenic/antiestrogenic properties.

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Year:  1991        PMID： 1665776     DOI： 10.1016/0010-7824(91)90157-b

Source DB:  PubMed          Journal:  Contraception        ISSN： 0010-7824            Impact factor:   3.375


  5 in total

1.  XIAP inhibitor and antiestrogen embelin abrogates metastasis and augments apoptosis in estrogen receptor positive human breast adenocarcinoma cell line MCF-7.

Authors:  K R Sumalatha; G Abiramasundari; G K Chetan; T Divya; G Sudhandiran; M Sreepriya
Journal:  Mol Biol Rep       Date:  2014-01-04       Impact factor: 2.316

2.  Isolation and identification of mosquito larvicidal compound from Abutilon indicum (Linn.) Sweet.

Authors:  A Abdul Rahuman; Geetha Gopalakrishnan; P Venkatesan; Kannappan Geetha
Journal:  Parasitol Res       Date:  2008-01-03       Impact factor: 2.289

3.  Evaluation of protective effect of Butea monosperma (lam.) Taub in experimental hepatotoxicity in rats.

Authors:  Arti Gupta; N R Sheth; Sonia Pandey; Jitendra S Yadav; D R Shah; B Vyas; S Joshi
Journal:  J Pharmacol Pharmacother       Date:  2012-04

4.  Activation of p38/JNK pathway is responsible for embelin induced apoptosis in lung cancer cells: transitional role of reactive oxygen species.

Authors:  Deepa R Avisetti; K Suresh Babu; Shasi V Kalivendi
Journal:  PLoS One       Date:  2014-01-22       Impact factor: 3.240

Review 5.  Ethnomedicinal, Phytochemical and Ethnopharmacological Aspects of Four Medicinal Plants of Malvaceae Used in Indian Traditional Medicines: A Review.

Authors:  Jasmeet Kaur Abat; Sanjay Kumar; Aparajita Mohanty
Journal:  Medicines (Basel)       Date:  2017-10-18
  5 in total

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