| Literature DB >> 1665342 |
C Montalban1, C Bellas, J L Rodriguez-Garcia, M Aguado, R Fernandez-Muñoz.
Abstract
Hodgkin's disease was diagnosed in a 22-year-old HIV-seropositive man in 1986. Alternate MOPP/ABVD chemotherapy induced a clinical remission. He was asymptomatic until 3 years later when fever and peripheral and mediastinal lymphadenopathy appeared. Lymph node biopsy showed a large-cell anaplastic lymphoma and EBV genome was identified in the malignant cells, suggesting that transformation might had been induced by EBV. The present case affirms that in patients with HIV-related lymphomas who present enlarging lymphadenopathy after stable remission, the development of lymphomas of higher malignancy needs to be ruled out.Entities:
Keywords: Antimetabolites; Biology; Case Histories; Data Collection; Developed Countries; Diseases; Europe; Hiv Infections; Ingredients And Chemicals; Mediterranean Countries; Metabolic Effects; Mustard Compounds; Neoplasms; Organic Chemicals; Physiology; Research Methodology; Southern Europe; Spain; Viral Diseases
Mesh：
Year: 1991 PMID： 1665342 DOI： 10.1093/oxfordjournals.annonc.a058025
Source DB: PubMed Journal: Ann Oncol ISSN： 0923-7534 Impact factor: 32.976