Literature DB >> 16652093

FDG-PET in the clinically negative neck in oral squamous cell carcinoma.

Bart M Wensing1, Wouter V Vogel, Henri A M Marres, Matthias A W Merkx, Ernst J Postema, Wim J G Oyen, Frank J A van den Hoogen.   

Abstract

OBJECTIVE: With improved diagnostic imaging techniques, it remains difficult to reduce occult metastatic disease in oral squamous cell carcinoma (SCC) to less than 20%. Therefore, supraomohyoid neck dissection (SOHND) still is a valuable staging procedure in these patients.
METHODS: Patients with clinically and ultrasonographically staged cN0 SCC of the oral cavity underwent FDG-PET before SOHND. Histologic examination of neck dissection specimens was used as a "gold standard."
RESULTS: Twenty-eight consecutive patients were included, representing 30 necks. Occult metastatic disease was found in 30% of SOHND specimens. Average diameter of metastatic deposits was 4.3 mm. Sensitivity, specificity, and accuracy of FDG-PET was 33%, 76%, and 63%, respectively.
CONCLUSIONS: In patients with cN0 SCC of the oral cavity, FDG-PET does not contribute to the preoperative workup. FDG-PET does not replace SOHND as a staging procedure.

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Year:  2006        PMID: 16652093     DOI: 10.1097/01.mlg.0000209151.78362.d0

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  6 in total

1.  The potential of FDG-PET in the detection of occult lymph node metastasis: importance of patient selection and reference standard.

Authors:  Remco de Bree; Otto S Hoekstra
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-02-08       Impact factor: 2.503

2.  Positron emission tomography-CT prediction of occult nodal metastasis in recurrent laryngeal cancer.

Authors:  Andrew Rosko; Andrew Birkeland; Andrew Shuman; Mark Prince; Carol Bradford; Gregory Wolf; Francis Worden; Avraham Eisbruch; Ashok Srinivasan; Ka Kit Wong; Matthew E Spector
Journal:  Head Neck       Date:  2017-02-25       Impact factor: 3.147

3.  Preoperative [18F]-fluorodeoxyglucose positron emission tomography standardized uptake value of neck lymph nodes may aid in selecting patients with oral cavity squamous cell carcinoma for salvage therapy after relapse.

Authors:  Chun-Ta Liao; Joseph Tung-Chieh Chang; Hung-Ming Wang; Shu-Hang Ng; Shiang-Fu Huang; I-How Chen; Chuen Hsueh; Li-Yu Lee; Chih-Hung Lin; Ann-Joy Cheng; Tzu-Chen Yen
Journal:  Eur J Nucl Med Mol Imaging       Date:  2009-06-04       Impact factor: 9.236

4.  Staging of untreated nasopharyngeal carcinoma with PET/CT: comparison with conventional imaging work-up.

Authors:  Shu-Hang Ng; Sheng-Chieh Chan; Tzu-Chen Yen; Joseph Tung-Chieh Chang; Chun-Ta Liao; Sheung-Fat Ko; Feng-Yuan Liu; Shu-Chyn Chin; Kang-Hsing Fan; Cheng-Lung Hsu
Journal:  Eur J Nucl Med Mol Imaging       Date:  2008-08-15       Impact factor: 9.236

5.  Pre-treatment levels of C-reactive protein and squamous cell carcinoma antigen for predicting the aggressiveness of pharyngolaryngeal carcinoma.

Authors:  Hsuan-Ho Chen; Hung-Ming Wang; Kang-Hsing Fan; Chien-Yu Lin; Tzu-Chen Yen; Chun-Ta Liao; I-How Chen; Chung-Jan Kang; Shiang-Fu Huang
Journal:  PLoS One       Date:  2013-01-31       Impact factor: 3.240

6.  Distant metastases and synchronous malignancies on FDG-PET/CT in patients with head and neck cancer: a retrospective study.

Authors:  Lennart Flygare; Amal Al-Ubaedi; Wilhelm Öhman; Susanna Jakobson Mo
Journal:  Acta Radiol       Date:  2020-01-05       Impact factor: 1.990

  6 in total

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