Literature DB >> 1665115

Detecting fabrication of data in a multicenter collaborative animal study.

K R Bailey1.   

Abstract

In 1980-1981 the National Heart, Lung, and Blood Institute (NHLBI) sponsored a multicenter study of animal models for protection of ischemic myocardium (AMPIM). After data collection for the study was complete, problems were identified with data from one of the labs. This article deals with the issue of statistical evidence versus hard evidence as well as the process of crossing the boundary from suspicion to certainty regarding the nature and extent of the problem.

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Year:  1991        PMID: 1665115     DOI: 10.1016/0197-2456(91)90037-m

Source DB:  PubMed          Journal:  Control Clin Trials        ISSN: 0197-2456


  7 in total

1.  Statistics and ethics in medical research.

Authors:  David L DeMets
Journal:  Sci Eng Ethics       Date:  1999-01       Impact factor: 3.525

2.  Clinical trials: To catch a crook, you might try statistics.

Authors:  Gary R Cutter
Journal:  Nat Rev Neurol       Date:  2016-12-16       Impact factor: 42.937

3.  Monitoring clinical research: an obligation unfulfilled.

Authors:  C Weijer; S Shapiro; A Fuks; K C Glass; M Skrutkowska
Journal:  CMAJ       Date:  1995-06-15       Impact factor: 8.262

Review 4.  Bringing rigour to translational medicine.

Authors:  David W Howells; Emily S Sena; Malcolm R Macleod
Journal:  Nat Rev Neurol       Date:  2013-11-19       Impact factor: 42.937

5.  Prof Benchie and Dr Athena-A modern tragedy….

Authors:  Malcolm Macleod
Journal:  Evid Based Preclin Med       Date:  2015-06-27

6.  SERE: single-parameter quality control and sample comparison for RNA-Seq.

Authors:  Stefan K Schulze; Rahul Kanwar; Meike Gölzenleuchter; Terry M Therneau; Andreas S Beutler
Journal:  BMC Genomics       Date:  2012-10-03       Impact factor: 3.969

7.  How does correlation structure differ between real and fabricated data-sets?

Authors:  Noori Akhtar-Danesh; Mahshid Dehghan-Kooshkghazi
Journal:  BMC Med Res Methodol       Date:  2003-09-29       Impact factor: 4.615

  7 in total

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