Literature DB >> 16650668

Prevalence and risk factors of lens opacities in urban and rural Chinese in Beijing.

Liang Xu1, Tongtong Cui, Shiyuan Zhang, Baochen Sun, Yuanyuan Zheng, Ailian Hu, Jianjun Li, Ke Ma, Jost B Jonas.   

Abstract

OBJECTIVE: To determine the prevalence of lens opacities in the elderly Chinese population in an urban and a rural region of Beijing.
DESIGN: Population-based cross-sectional study. PARTICIPANTS: The study included 4439 subjects of 5324 subjects invited to participate (response rate, 83.4%). The subjects were divided into a rural part (1973 subjects [44.4%]) and an urban part (2466 subjects [55.6%]). The study was limited to participants age 40 and older, and the mean age was 56.2+/-10.6 years (range, 40-101 years).
METHODS: Nuclear, cortical, and posterior subcapsular lens opacities were assessed based on standardized slit-lamp photographs of the lens using a modification of the grading score of the Age-related Eye Disease Study (AREDS). MAIN OUTCOME MEASURES: Grading score of the AREDS.
RESULTS: Lens data were provided for 4378 subjects (98.6%) of 4439 persons examined, which consisted of 8724 eyes. Prevalence of any cataract surgery was 1.3% (95% confidence interval [CI]: 1.0-1.7), which was statistically independent of gender (P = 0.51; odds ratio [OR]: 0.86; 95% CI: 1.00-1.34), rural area versus urban region (P = 0.25), and level of education (P = 0.84). Prevalence of any nuclear lens opacity was 82.0% (95% CI: 80.8-83.2); prevalence of any cortical lens opacity was 10.3% (95% CI: 9.4-11.3); and prevalence of any posterior subcapsular opacity was 4.3% (95% CI: 3.7-4.9). If grade 2 of nuclear lens opacity was considered to be normal, prevalence of nuclear cataract was 50.3% (95% CI: 48.8-51.8), and the overall prevalence of any cataract was 53.1% (95% CI: 51.6-54.6), increasing from 6.5% (95% CI: 5.2-7.8) in those subjects 40 to 49 years of age to 52.3% (95% CI: 47.4-55.3) in those who were 50 to 59 years of age, and to 97.8% (95% CI: 96.4-99.2) in those 70 years and older (P<0.001). Frequencies of any cortical cataract and any subcapsular posterior cataract were 10.3% (95% CI: 9.4-11.3) and 4.3% (95% CI: 3.7-4.9), respectively.
CONCLUSIONS: Cataracts are common among adult Chinese residents in Beijing, with age as the most important associated factor. In view of the relatively low rate of cataract surgery performed so far, one may expect a marked increase in the number of cataract surgeries to meet the visual needs of the growing elderly population in China.

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Year:  2006        PMID: 16650668     DOI: 10.1016/j.ophtha.2006.01.026

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  28 in total

1.  Central corneal thickness and retinal vein occlusions: the Beijing Eye Study.

Authors:  Liang Xu; Qi Sheng You; Jost B Jonas
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2009-10-22       Impact factor: 3.117

2.  Relationship between socioeconomic and lifestyle factors and cataracts in Koreans: the Korea National Health and Nutrition Examination Survey 2008-2011.

Authors:  G E Nam; K Han; S G Ha; B-D Han; D H Kim; Y-H Kim; K H Cho; Y G Park; B-J Ko
Journal:  Eye (Lond)       Date:  2015-05-15       Impact factor: 3.775

3.  Associated factors for age related maculopathy in the adult population in China: the Beijing eye study.

Authors:  L Xu; Y Li; Y Zheng; J B Jonas
Journal:  Br J Ophthalmol       Date:  2006-06-14       Impact factor: 4.638

Review 4.  Global and regional prevalence of age-related cataract: a comprehensive systematic review and meta-analysis.

Authors:  Hassan Hashemi; Reza Pakzad; Abbasali Yekta; Mohamadreza Aghamirsalim; Mojgan Pakbin; Shahroukh Ramin; Mehdi Khabazkhoob
Journal:  Eye (Lond)       Date:  2020-02-13       Impact factor: 3.775

5.  Association between asymmetry in cataract and asymmetry in age-related macular degeneration. The Beijing Eye Study.

Authors:  Liang Xu; Qi Sheng You; Tongtong Cui; Jost B Jonas
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2010-12-21       Impact factor: 3.117

6.  The prevalence of retinal vein occlusion: pooled data from population studies from the United States, Europe, Asia, and Australia.

Authors:  Sophie Rogers; Rachel L McIntosh; Ning Cheung; Lyndell Lim; Jie Jin Wang; Paul Mitchell; Jonathan W Kowalski; Hiep Nguyen; Tien Y Wong
Journal:  Ophthalmology       Date:  2010-02       Impact factor: 12.079

7.  Association between gap junction protein-alpha 8 polymorphisms and age-related cataract.

Authors:  Yuanyuan Liu; Min Ke; Ming Yan; Shuren Guo; Mane Emily Mothobi; Qiang Chen; Fang Zheng
Journal:  Mol Biol Rep       Date:  2010-06-27       Impact factor: 2.316

8.  Level of education associated with ophthalmic diseases. The Beijing Eye Study.

Authors:  Liang Xu; Ya Xing Wang; Jost B Jonas
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2009-10-11       Impact factor: 3.117

9.  Unexpected potential protective associations between outdoor air pollution and cataracts.

Authors:  Yoon-Hyeong Choi; Su Jin Park; Hae Jung Paik; Mee Kum Kim; Won Ryang Wee; Dong Hyun Kim
Journal:  Environ Sci Pollut Res Int       Date:  2018-02-01       Impact factor: 4.223

10.  Cataract and mortality. The Beijing eye study.

Authors:  Liang Xu; Tong Tong Cui; Ya Xing Wang; Jost B Jonas
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-01-12       Impact factor: 3.117

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