David Parada1, Karla Peña, Otto Moreira. 1. Service of Pathology, Vargas Hospital, José María Vargas School of Medicine, Central University of Venezuela, Caracas. parada@cantv.net
Abstract
OBJECTIVES: We report herein the clinical, histological, and immunohistochemical features of a case of sarcomatoid chromophobe renal cell carcinoma. METHODS/ RESULTS: A 59-year-old woman referred a two-month history of constant right flank pain, and hematuria. A right radical nephrectomy was performed. Gross pathologic examination showed a tumor located in the lower part of the kidney with two different aspects. Histologically, the tumor was composed of two intermixed distinct morphologic components: a chromophobe renal cell carcinoma and a high-grade spindle cell sarcoma. CONCLUSION: Our case represent a typical sarcomatoid chromophobe cell carcinoma. This unusual renal cancer has the potential to behave aggressively and to metastasize.
OBJECTIVES: We report herein the clinical, histological, and immunohistochemical features of a case of sarcomatoid chromophobe renal cell carcinoma. METHODS/ RESULTS: A 59-year-old woman referred a two-month history of constant right flank pain, and hematuria. A right radical nephrectomy was performed. Gross pathologic examination showed a tumor located in the lower part of the kidney with two different aspects. Histologically, the tumor was composed of two intermixed distinct morphologic components: a chromophobe renal cell carcinoma and a high-grade spindle cell sarcoma. CONCLUSION: Our case represent a typical sarcomatoid chromophobe cell carcinoma. This unusual renal cancer has the potential to behave aggressively and to metastasize.
Authors: Jindong Chen; Dachuan Huang; Isabelle Rubera; Kunihiko Futami; Pengfei Wang; Peter Zickert; Sok-Kean Khoo; Karl Dykema; Ping Zhao; David Petillo; Brian Cao; Zhongfa Zhang; Shuhui Si; Susan R Schoen; Ximing J Yang; Ming Zhou; Guang-Qian Xiao; Guan Wu; Magnus Nordenskjöld; Michel Tauc; Bart O Williams; Kyle A Furge; Bin Tean Teh Journal: Kidney Int Date: 2015-06-17 Impact factor: 10.612