BACKGROUND: Few randomised controlled trials have been aimed specifically at substance use reduction among people with psychotic disorders. AIMS: To investigate whether a 10-session intervention consisting of motivational interviewing and cognitive-behavioural therapy (CBT) was more efficacious than routine treatment in reducing substance use and improving symptomatology and general functioning. METHOD: A community sample of people with a psychotic disorder and who reported hazardous alcohol, cannabis and/or amphetamine use during the preceding month was recruited. Participants were randomly allocated to motivational interviewing/CBT (n = 65) or treatment as usual (n = 65), and were assessed on multiple outcomes at baseline, 15 weeks, 6 months and 12 months. RESULTS: There was a short-term improvement in depression and a similar trend with regard to cannabis use among participants who received the motivational interviewing/CBT intervention, together with effects on general functioning at 12 months. There was no differential benefit of the intervention on substance use at 12 months, except for a potentially clinically important effect on amphetamine use. CONCLUSIONS: The motivational interviewing/CBT intervention was associated with modest improvements.
RCT Entities:
BACKGROUND: Few randomised controlled trials have been aimed specifically at substance use reduction among people with psychotic disorders. AIMS: To investigate whether a 10-session intervention consisting of motivational interviewing and cognitive-behavioural therapy (CBT) was more efficacious than routine treatment in reducing substance use and improving symptomatology and general functioning. METHOD: A community sample of people with a psychotic disorder and who reported hazardous alcohol, cannabis and/or amphetamine use during the preceding month was recruited. Participants were randomly allocated to motivational interviewing/CBT (n = 65) or treatment as usual (n = 65), and were assessed on multiple outcomes at baseline, 15 weeks, 6 months and 12 months. RESULTS: There was a short-term improvement in depression and a similar trend with regard to cannabis use among participants who received the motivational interviewing/CBT intervention, together with effects on general functioning at 12 months. There was no differential benefit of the intervention on substance use at 12 months, except for a potentially clinically important effect on amphetamine use. CONCLUSIONS: The motivational interviewing/CBT intervention was associated with modest improvements.
Authors: Frank N Angelo; Michael G McDonell; Michael R Lewin; Debra Srebnik; Jessica Lowe; John Roll; Richard Ries Journal: Drug Alcohol Depend Date: 2012-12-27 Impact factor: 4.492
Authors: Sean M Murphy; Michael G McDonell; Sterling McPherson; Debra Srebnik; Frank Angelo; John M Roll; Richard K Ries Journal: Drug Alcohol Depend Date: 2015-05-14 Impact factor: 4.492
Authors: Lisa B Dixon; Faith Dickerson; Alan S Bellack; Melanie Bennett; Dwight Dickinson; Richard W Goldberg; Anthony Lehman; Wendy N Tenhula; Christine Calmes; Rebecca M Pasillas; Jason Peer; Julie Kreyenbuhl Journal: Schizophr Bull Date: 2009-12-02 Impact factor: 9.306
Authors: Clara M Bradizza; Stephen A Maisto; Paula C Vincent; Paul R Stasiewicz; Gerard J Connors; Nicole D Mercer Journal: J Consult Clin Psychol Date: 2009-12