Literature DB >> 1664785

Research priorities for diarrhoeal disease vaccines: memorandum from a WHO meeting.

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Abstract

Diarrhoeas caused by rotaviruses, Shigella, Vibrio cholerae, and enterotoxigenic Escherichia coli (ETEC) represent a major health burden in developing countries, and have stimulated much effort towards vaccine development in order to protect against these four disease agents. This Memorandum describes the state of the art and points the way to future research and test trials in this area.

Entities:  

Keywords:  Americas; Bacterial And Fungal Diseases; Clinical Research; Clinical Trials; Developed Countries; Developing Countries; Diarrhea; Diseases; Economic Factors; Infections; International Agencies; Needs; North America; Northern America; Organizations; Recommendations; Research And Development; Research Methodology; Technology; Un; United States; Vaccines; Viral Diseases; Who

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Substances:

Year:  1991        PMID: 1664785      PMCID: PMC2393325     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  5 in total

1.  Serotype 1a O-antigen modification: molecular characterization of the genes involved and their novel organization in the Shigella flexneri chromosome.

Authors:  P Adhikari; G Allison; B Whittle; N K Verma
Journal:  J Bacteriol       Date:  1999-08       Impact factor: 3.490

2.  Why does the world need another rotavirus vaccine?

Authors:  Richard L Ward; Monica M McNeal; A Duncan Steele
Journal:  Ther Clin Risk Manag       Date:  2008-02       Impact factor: 2.423

3.  Regulated Delayed Shigella flexneri 2a O-antigen Synthesis in Live Recombinant Salmonella enterica Serovar Typhimurium Induces Comparable Levels of Protective Immune Responses with Constitutive Antigen Synthesis System.

Authors:  Huali Su; Qing Liu; Shifeng Wang; Roy Curtiss; Qingke Kong
Journal:  Theranostics       Date:  2019-05-26       Impact factor: 11.556

4.  What Drives the Value of a Shigella Vaccine?

Authors:  William P Hausdorff; Suzanne Scheele; Birgitte K Giersing
Journal:  Vaccines (Basel)       Date:  2022-02-12

5.  A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit.

Authors:  M Pizza; M R Fontana; M M Giuliani; M Domenighini; C Magagnoli; V Giannelli; D Nucci; W Hol; R Manetti; R Rappuoli
Journal:  J Exp Med       Date:  1994-12-01       Impact factor: 14.307

  5 in total

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