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Literature DB >> 16647064

The role of molecular modelling in biomedical research.

Abstract

The synergy between experimental and computational biology has greatly benefited both fields, providing invaluable information in many different areas of the life sciences. This minireview will focus on one specific aspect of computational biology, molecular modelling, and describe a few examples highlighting the effectiveness of protein structural analysis and modelling in providing relevant information about systems of biomedical interest.

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Year: 2006 PMID： 16647064 DOI： 10.1016/j.febslet.2006.04.011

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

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Cited

8 in total

1. Evaluation of model quality predictions in CASP9.

Authors: Andriy Kryshtafovych; Krzysztof Fidelis; Anna Tramontano
Journal: Proteins Date: 2011-10-14

2. Computational models in the service of X-ray and cryo-electron microscopy structure determination.

Authors: Andriy Kryshtafovych; John Moult; Reinhard Albrecht; Geoffrey A Chang; Kinlin Chao; Alec Fraser; Julia Greenfield; Marcus D Hartmann; Osnat Herzberg; Inokentijs Josts; Petr G Leiman; Sara B Linden; Andrei N Lupas; Daniel C Nelson; Steven D Rees; Xiaoran Shang; Maria L Sokolova; Henning Tidow
Journal: Proteins Date: 2021-09-06

3. Outcome of a workshop on applications of protein models in biomedical research.

Authors: Torsten Schwede; Andrej Sali; Barry Honig; Michael Levitt; Helen M Berman; David Jones; Steven E Brenner; Stephen K Burley; Rhiju Das; Nikolay V Dokholyan; Roland L Dunbrack; Krzysztof Fidelis; Andras Fiser; Adam Godzik; Yuanpeng Janet Huang; Christine Humblet; Matthew P Jacobson; Andrzej Joachimiak; Stanley R Krystek; Tanja Kortemme; Andriy Kryshtafovych; Gaetano T Montelione; John Moult; Diana Murray; Roberto Sanchez; Tobin R Sosnick; Daron M Standley; Terry Stouch; Sandor Vajda; Max Vasquez; John D Westbrook; Ian A Wilson
Journal: Structure Date: 2009-02-13 Impact factor: 5.006

The role of molecular modelling in biomedical research.

1. Evaluation of model quality predictions in CASP9.

2. Computational models in the service of X-ray and cryo-electron microscopy structure determination.

3. Outcome of a workshop on applications of protein models in biomedical research.

4. Mathematical modeling of viral infection dynamics in spherical organs.

5. Assessment of the assessment: evaluation of the model quality estimates in CASP10.

6. Pockets as structural descriptors of EGFR kinase conformations.

Review 7. Protein function annotation by homology-based inference.

8. A kernel for open source drug discovery in tropical diseases.