Literature DB >> 16646104

Organocatalytic conjugate addition of malonates to alpha,beta-unsaturated aldehydes: asymmetric formal synthesis of (-)-paroxetine, chiral lactams, and lactones.

Sven Brandau1, Aitor Landa, Johan Franzén, Mauro Marigo, Karl Anker Jørgensen.   

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Year:  2006        PMID： 16646104     DOI： 10.1002/anie.200601025

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  15 in total

1.  A green chemistry approach to asymmetric catalysis: solvent-free and highly concentrated reactions.

Authors:  Patrick J Walsh; Hongmei Li; Cecilia Anaya de Parrodi
Journal:  Chem Rev       Date:  2007-05-27       Impact factor: 60.622

2.  A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter.

Authors:  Rachel D Slack; Ara M Abramyan; Helen Tang; Sitaram Meena; Bruce A Davis; Alessandro Bonifazi; JoLynn B Giancola; Jeffrey R Deschamps; Sett Naing; Hideaki Yano; Satinder K Singh; Amy Hauck Newman; Lei Shi
Journal:  ACS Chem Neurosci       Date:  2019-08-22       Impact factor: 4.418

3.  A general organocatalyzed Michael-Michael cascade reaction generates functionalized cyclohexenes.

Authors:  Patrick G McGarraugh; Joshua H Jones; Stacey E Brenner-Moyer
Journal:  J Org Chem       Date:  2011-07-08       Impact factor: 4.354

4.  Organocatalytic enantioselective β-functionalization of aldehydes by oxidation of enamines and their application in cascade reactions.

Authors:  Shi-Lei Zhang; He-Xin Xie; Jin Zhu; Hao Li; Xin-Shuai Zhang; Jian Li; Wei Wang
Journal:  Nat Commun       Date:  2011       Impact factor: 14.919

5.  CuH-Catalyzed Asymmetric Reduction of α,β-Unsaturated Carboxylic Acids to β-Chiral Aldehydes.

Authors:  Yujing Zhou; Jeffrey S Bandar; Richard Y Liu; Stephen L Buchwald
Journal:  J Am Chem Soc       Date:  2018-01-04       Impact factor: 15.419

6.  Chemical and structural investigation of the paroxetine-human serotonin transporter complex.

Authors:  Jonathan A Coleman; Vikas Navratna; Daniele Antermite; Dongxue Yang; James A Bull; Eric Gouaux
Journal:  Elife       Date:  2020-07-03       Impact factor: 8.140

Review 7.  Photochemical and Electrochemical Applications of Proton-Coupled Electron Transfer in Organic Synthesis.

Authors:  Philip R D Murray; James H Cox; Nicholas D Chiappini; Casey B Roos; Elizabeth A McLoughlin; Benjamin G Hejna; Suong T Nguyen; Hunter H Ripberger; Jacob M Ganley; Elaine Tsui; Nick Y Shin; Brian Koronkiewicz; Guanqi Qiu; Robert R Knowles
Journal:  Chem Rev       Date:  2021-11-23       Impact factor: 60.622

8.  Rapid Construction of (-)-Paroxetine and (-)-Femoxetine via N-Heterocyclic Carbene Catalyzed Homoenolate Addition to Nitroalkenes.

Authors:  Nicholas A White; Kerem E Ozboya; Darrin M Flanigan; Tomislav Rovis
Journal:  Asian J Org Chem       Date:  2014-04       Impact factor: 3.319

9.  Asymmetric synthesis of functionalized cyclopentanones via a multicatalytic secondary amine/N-heterocyclic carbene catalyzed cascade sequence.

Authors:  Stephen P Lathrop; Tomislav Rovis
Journal:  J Am Chem Soc       Date:  2009-09-30       Impact factor: 15.419

Review 10.  Asymmetric organocatalysis at the service of medicinal chemistry.

Authors:  Alfredo Ricci
Journal:  ISRN Org Chem       Date:  2014-03-11
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