Literature DB >> 16645899

Gastric H,K-ATPase as a drug target.

Jai Moo Shin1, George Sachs.   

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Year:  2006        PMID： 16645899     DOI： 10.1007/s10620-005-9042-8

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN： 0163-2116            Impact factor:   3.199


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  55 in total

1.  The H,K-ATPase beta subunit as a model to study the role of N-glycosylation in membrane trafficking and apical sorting.

Authors:  Olga Vagin; Shahlo Turdikulova; George Sachs
Journal:  J Biol Chem       Date:  2004-07-07       Impact factor: 5.157

2.  Regions of association between the alpha and the beta subunit of the gastric H,K-ATPase.

Authors:  D Melle-Milovanovic; M Milovanovic; S Nagpal; G Sachs; J M Shin
Journal:  J Biol Chem       Date:  1998-05-01       Impact factor: 5.157

3.  Differences in pH-dependent activation rates of substituted benzimidazoles and biological in vitro correlates.

Authors:  W Kromer; U Krüger; R Huber; M Hartmann; V W Steinijans
Journal:  Pharmacology       Date:  1998-02       Impact factor: 2.547

4.  Mutational analysis of the K+-competitive inhibitor site of gastric H,K-ATPase.

Authors:  O Vagin; K Munson; N Lambrecht; S J Karlish; G Sachs
Journal:  Biochemistry       Date:  2001-06-26       Impact factor: 3.162

5.  Molecular cloning and structural analysis of canine gastric H+,K(+)-ATPase.

Authors:  I Song; M P Mortell; I Gantz; D R Brown; T Yamada
Journal:  Biochem Biophys Res Commun       Date:  1993-11-15       Impact factor: 3.575

Review 6.  The continuing development of gastric acid pump inhibitors.

Authors:  G Sachs; J M Shin; M Besancon; C Prinz
Journal:  Aliment Pharmacol Ther       Date:  1993       Impact factor: 8.171

7.  Identification of a region of the H,K-ATPase alpha subunit associated with the beta subunit.

Authors:  J M Shin; G Sachs
Journal:  J Biol Chem       Date:  1994-03-25       Impact factor: 5.157

8.  Inhibitor and ion binding sites on the gastric H,K-ATPase.

Authors:  Keith Munson; Rachel Garcia; George Sachs
Journal:  Biochemistry       Date:  2005-04-12       Impact factor: 3.162

9.  Turnover of the gastric H+,K(+)-adenosine triphosphatase alpha subunit and its effect on inhibition of rat gastric acid secretion.

Authors:  K Gedda; D Scott; M Besancon; P Lorentzon; G Sachs
Journal:  Gastroenterology       Date:  1995-10       Impact factor: 22.682

10.  SCH 28080 is a lumenally acting, K+-site inhibitor of the gastric (H+ + K+)-ATPase.

Authors:  D J Keeling; S M Laing; J Senn-Bilfinger
Journal:  Biochem Pharmacol       Date:  1988-06-01       Impact factor: 5.858
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  7 in total

Review 1.  The renal H+-K+-ATPases: physiology, regulation, and structure.

Authors:  Michelle L Gumz; I Jeanette Lynch; Megan M Greenlee; Brian D Cain; Charles S Wingo
Journal:  Am J Physiol Renal Physiol       Date:  2009-07-29

2.  ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia.

Authors:  Peter Walentek; Tina Beyer; Cathrin Hagenlocher; Christina Müller; Kerstin Feistel; Axel Schweickert; Richard M Harland; Martin Blum
Journal:  Dev Biol       Date:  2015-04-04       Impact factor: 3.582

3.  A high-throughput scintillation proximity-based assay for human DNA ligase IV.

Authors:  Hui-Min Tseng; David Shum; Bhavneet Bhinder; Sindy Escobar; Nicholas J Veomett; Alan E Tomkinson; David Y Gin; Hakim Djaballah; David A Scheinberg
Journal:  Assay Drug Dev Technol       Date:  2011-12-22       Impact factor: 1.738

4.  Computational insights into the interaction mechanism of triazolyl substituted tetrahydrobenzofuran derivatives with H(+),K(+)-ATPase at different pH.

Authors:  Hua-Jun Luo; Jun-Zhi Wang; Nian-Yu Huang; Wei-Qiao Deng; Kun Zou
Journal:  J Comput Aided Mol Des       Date:  2015-12-14       Impact factor: 3.686

5.  Protonated form: the potent form of potassium-competitive acid blockers.

Authors:  Hua-Jun Luo; Wei-Qiao Deng; Kun Zou
Journal:  PLoS One       Date:  2014-05-20       Impact factor: 3.240

Review 6.  Potassium Channelopathies and Gastrointestinal Ulceration.

Authors:  Jaeyong Han; Seung Hun Lee; Gerhard Giebisch; Tong Wang
Journal:  Gut Liver       Date:  2016-11-15       Impact factor: 4.519

7.  Impact of Gastric H+/K+-ATPase rs2733743 on the Intragastric pH-Values of Dexlansoprazole Injection in Chinese Subjects.

Authors:  Lu-Ning Sun; Yang Cao; Yue-Qi Li; Yun-Qian Fang; Hong-Wen Zhang; Mei-Feng Wang; Li-Jun Xie; Juan Chen; Zhi-Cheng Yang; Ming-Liang Bian; Hao Li; Pei-Pei Zhang; Ji-Fu Wei; Ling Meng; Xue-Hui Zhang; Ping Zhao; Yong-Qing Wang
Journal:  Front Pharmacol       Date:  2017-09-22       Impact factor: 5.810
  7 in total

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