Literature DB >> 1664468

Immunohistochemical detection of HBsAg and HBcAg in the liver of patients with schistosomiasis japonica complicated by hepatocellular carcinoma.

Z J Li1, D D Luo, J Z Dai, L L Zheng, X H Wang, S C Liu, G F Shong, Y X Yang, H C Wang.   

Abstract

In liver biopsies from 21 patients with schistosomiasis japonica complicated by hepatocellular carcinoma (HCC), 69 patients with advanced schistosomiasis japonica, and 25 patients with HCC, HBsAg and HBcAg were investigated with peroxidase-antiperoxidase technique. The positive rate of HBAg (i.e. HBsAg and/or HBcAg) in the liver of patients with schistosomiasis japonica complicated by HCC was significantly higher than in the group of advanced schistosomiasis japonica, but similar to that in cases of HCC. The location of carcinoma cells in the liver was not related to the distribution of Schistosoma ova in patients with schistosomiasis japonica complicated by HCC. The results indicated that the complication with hepatitis B virus infection may be one of the major factors involved in the development of HCC in patients with schistosomiasis japonica.

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Year:  1991        PMID: 1664468     DOI: 10.1007/bf02888124

Source DB:  PubMed          Journal:  J Tongji Med Univ        ISSN: 0257-716X


  6 in total

1.  Primary liver cancer coincident with Schistosomiasis japonica. A study of 24 necropsies.

Authors:  T Nakashima; K Okuda; M Kojiro; K Sakamoto; Y Kubo
Journal:  Cancer       Date:  1975-10       Impact factor: 6.860

2.  A case-control study on liver cancer with special emphasis on the possible aetiological role of schistosomiasis.

Authors:  Y Inaba; N Maruchi; M Matsuda; N Yoshihara; S Yamamoto
Journal:  Int J Epidemiol       Date:  1984-12       Impact factor: 7.196

3.  [Primary liver cancer coincident with schistosomiasis japonica].

Authors:  S Uetsuji; M Yamamura; Y Okuda; K Yamamichi; M Yamamoto
Journal:  Gan No Rinsho       Date:  1990-03

4.  Hepatitis B surface antigen carrier state in hepatosplenic schistosomiasis.

Authors:  L G Lyra; G Rebouças; Z A Andrade
Journal:  Gastroenterology       Date:  1976-10       Impact factor: 22.682

5.  Liver cancer in an endemic area of schistosomiasis japonica in Yamanashi Prefecture, Japan.

Authors:  Y Inaba
Journal:  Princess Takamatsu Symp       Date:  1987

Review 6.  Schistosome infections in humans: perspectives and recent findings. NIH conference.

Authors:  T E Nash; A W Cheever; E A Ottesen; J A Cook
Journal:  Ann Intern Med       Date:  1982-11       Impact factor: 25.391

  6 in total

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