| Literature DB >> 16644541 |
J C Ndom1, J T Mbafor, J D Wansi, A W Kamdem, L M Meva'a, J C Vardamides, F Toukam, D Pegyemb, T M Ngando, H Laatsch, Z T Fomum.
Abstract
In addition to one known compound, 3beta,8alpha-dihydroxyguaian-4(15),10(14),11(13)-trien-6,12 olide (8-desacylcynaropicrin) (3), two new sesquiterpene lactones have been isolated from the aerial parts of Crepis cameroonica. By means of spectroscopic analysis, the structures and relative configurations of the new compounds were established as 3beta,9beta-dihydroxyguaian-4(15),10(14),11(13)-trien-6,12 olide (1) and 8alpha-hydroxy-4alpha(13),11beta(15)-tetrahydrozaluzanin C (2). The in vitro antimicrobial spectrum of pure compounds and crude extracts are also reported.Entities:
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Year: 2006 PMID: 16644541 DOI: 10.1080/14786410500182300
Source DB: PubMed Journal: Nat Prod Res ISSN: 1478-6419 Impact factor: 2.861