Literature DB >> 16644018

Proteome analysis to study signal transduction of G protein-coupled receptors.

Franka Pluder1, Karin Mörl, Annette G Beck-Sickinger.   

Abstract

G protein-coupled receptors (GPCR) play an important role in drug development. Although many classical signal transduction pathways have been elucidated, more and more cross-talk to other cascades, e.g. MAP-kinase have been reported. In order to identify the overall function of receptor stimulation in a specific cell type or under certain conditions proteome analysis has been shown to be a very successful and powerful approach. Here, we will summarize the current state of the art of proteome analysis applied to GPCR.

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Year:  2006        PMID： 16644018     DOI： 10.1016/j.pharmthera.2006.03.001

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN： 0163-7258            Impact factor:   12.310


  9 in total

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Authors:  Pascal Maurice; Avais M Daulat; Cédric Broussard; Julien Mozo; Guilhem Clary; Françoise Hotellier; Philippe Chafey; Jean-Luc Guillaume; Gilles Ferry; Jean A Boutin; Philippe Delagrange; Luc Camoin; Ralf Jockers
Journal:  Mol Cell Proteomics       Date:  2008-04-29       Impact factor: 5.911

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Authors:  Gregory E Bigford; Nauman S Chaudhry; Robert W Keane; Alice M Holohean
Journal:  J Biol Chem       Date:  2012-01-30       Impact factor: 5.157

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Review 5.  The role of Gbetagamma subunits in the organization, assembly, and function of GPCR signaling complexes.

Authors:  Denis J Dupré; Mélanie Robitaille; R Victor Rebois; Terence E Hébert
Journal:  Annu Rev Pharmacol Toxicol       Date:  2009       Impact factor: 13.820

Review 6.  Studying protein-protein affinity and immobilized ligand-protein affinity interactions using MS-based methods.

Authors:  Jeroen Kool; Niels Jonker; Hubertus Irth; Wilfried M A Niessen
Journal:  Anal Bioanal Chem       Date:  2011-07-14       Impact factor: 4.142

7.  Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis.

Authors:  Brady K Atwood; Jacqueline Lopez; James Wager-Miller; Ken Mackie; Alex Straiker
Journal:  BMC Genomics       Date:  2011-01-07       Impact factor: 3.969

8.  Identification of GPCR-interacting cytosolic proteins using HDL particles and mass spectrometry-based proteomic approach.

Authors:  Ka Young Chung; Peter W Day; Gisselle Vélez-Ruiz; Roger K Sunahara; Brian K Kobilka
Journal:  PLoS One       Date:  2013-01-25       Impact factor: 3.240

9.  Serial dilution curve: a new method for analysis of reverse phase protein array data.

Authors:  Li Zhang; Qingyi Wei; Li Mao; Wenbin Liu; Gordon B Mills; Kevin Coombes
Journal:  Bioinformatics       Date:  2009-01-28       Impact factor: 6.937
  9 in total

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