Literature DB >> 16643871

Synthesis of cancer-associated glycoantigens: stage-specific embryonic antigen 3 (SSEA-3).

Papapida Pornsuriyasak1, Alexei V Demchenko.   

Abstract

The synthesis of the tumor-associated carbohydrate antigens SSEA-3 and Gb3 in a semi-convergent fashion using building blocks bearing a S-thiazolinyl (STaz) moiety is reported. Complete stereoselective control of a difficult alpha-(1-->4)-galactosylation and high overall yields were achieved.

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Year:  2006        PMID： 16643871     DOI： 10.1016/j.carres.2006.03.041

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  3 in total

1.  Chemoenzymatic Syntheses of Tumor-Associated Carbohydrate Antigen Globo-H and Stage-Specific Embryonic Antigen 4.

Authors:  Zhen Wang; Michel Gilbert; Hironobu Eguchi; Hai Yu; Jiansong Cheng; Saddam Muthana; Luyuan Zhou; Peng George Wang; Xi Chen; Xuefei Huang
Journal:  Adv Synth Catal       Date:  2008-08-04       Impact factor: 5.837

2.  Glycosyl Thioimidates as Versatile Building Blocks for Organic Synthesis.

Authors:  S J Hasty; A V Demchenko
Journal:  Chem Heterocycl Compd (N Y)       Date:  2012-04       Impact factor: 1.277

3.  Multi-component one-pot synthesis of the tumor-associated carbohydrate antigen Globo-H based on preactivation of thioglycosyl donors.

Authors:  Zhen Wang; Luyuan Zhou; Kheireddine El-Boubbou; Xin-shan Ye; Xuefei Huang
Journal:  J Org Chem       Date:  2007-07-21       Impact factor: 4.354
  3 in total

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