OBJECTIVE: To summarize and evaluate available empirical research on the relationship between migraines and gestational hypertension or preeclampsia and to provide direction for future research in this area. BACKGROUND: Migraines affect a substantial proportion of reproductive-aged women and have been associated with cardiovascular risk factors and ischemic disease in this population. Preeclampsia is a vascular disorder of pregnancy, also linked to adverse cardiovascular outcomes. METHODS: Publications were identified by a MEDLINE search using keywords "migraine,""preeclampsia," and "gestational hypertension," and by examination of the reference lists of identified articles. RESULTS: The literature review yielded 10 studies addressing the association between migraines and preeclampsia or gestational hypertension. Of the 10 studies, 8 reported a positive association between the syndromes. CONCLUSIONS: Available evidence suggests that migraines and preeclampsia may reflect an underlying predisposition toward ischemic injury. More rigorous epidemiologic research is warranted, after consideration of several important methodologic issues.
OBJECTIVE: To summarize and evaluate available empirical research on the relationship between migraines and gestational hypertension or preeclampsia and to provide direction for future research in this area. BACKGROUND:Migraines affect a substantial proportion of reproductive-aged women and have been associated with cardiovascular risk factors and ischemic disease in this population. Preeclampsia is a vascular disorder of pregnancy, also linked to adverse cardiovascular outcomes. METHODS: Publications were identified by a MEDLINE search using keywords "migraine,""preeclampsia," and "gestational hypertension," and by examination of the reference lists of identified articles. RESULTS: The literature review yielded 10 studies addressing the association between migraines and preeclampsia or gestational hypertension. Of the 10 studies, 8 reported a positive association between the syndromes. CONCLUSIONS: Available evidence suggests that migraines and preeclampsia may reflect an underlying predisposition toward ischemic injury. More rigorous epidemiologic research is warranted, after consideration of several important methodologic issues.
Authors: Tarannum M Lateef; Lihong Cui; Karin B Nelson; Erin F Nakamura; Kathleen R Merikangas Journal: J Pediatr Date: 2012-02-28 Impact factor: 4.406
Authors: Michelle Vo; Abinnet Ainalem; Chunfang Qiu; B Lee Peterlin; Sheena K Aurora; Michelle A Williams Journal: Headache Date: 2011-01-26 Impact factor: 5.887
Authors: Michelle A Williams; B Lee Peterlin; Bizu Gelaye; Daniel A Enquobahrie; Raymond S Miller; Sheena K Aurora Journal: Headache Date: 2011-07-28 Impact factor: 5.887
Authors: Sixto E Sanchez; Michelle A Williams; Percy N Pacora; Cande V Ananth; Chungfang Qiu; Sheena K Aurora; Tanya K Sorensen Journal: BMC Womens Health Date: 2010-10-26 Impact factor: 2.809