Literature DB >> 166432

Latent infection of sensory ganglia with herpes simplex virus: efficacy of immunization.

R W Price, M A Walz, C Wohlenberg, A L Notkins.   

Abstract

Mice were used to test the efficacy of active immunization in preventing latent infection of local sensory ganglia that follows inoculation of superficial epithelial surfaces with herpes simplex virus. Substantial but not complete protection was observed in animals immunized and challenged with herpes simplex virus type 1, but no protection was noted in animals immunized and challenged with herpes simplex virus type 2. Latent ganglionic infection can develop in immunized animals despite the presence of high titers of neutralizing antibody.

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Year:  1975        PMID： 166432     DOI： 10.1126/science.166432

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  42 in total

1.  Effective vaccination against long-term gammaherpesvirus latency.

Authors:  Scott A Tibbetts; J Scott McClellan; Shivaprakash Gangappa; Samuel H Speck; Herbert W Virgin
Journal:  J Virol       Date:  2003-02       Impact factor: 5.103

2.  In vitro system for studying the efficacy of antiviral agents in preventing the reactivation of latent herpes simplex virus.

Authors:  C Wohlenberg; H Openshaw; A L Notkins
Journal:  Antimicrob Agents Chemother       Date:  1979-04       Impact factor: 5.191

3.  Host defenses in herpes simplex infections of the nervous system: effect of antibody on disease and viral spread.

Authors:  R R McKendall; T Klassen; J R Baringer
Journal:  Infect Immun       Date:  1979-02       Impact factor: 3.441

4.  Latent herpes simplex virus in ganglia of mice after primary infection and reinoculation at a distant site.

Authors:  R J Klein; A E Friedman-Kien; E Brady
Journal:  Arch Virol       Date:  1978       Impact factor: 2.574

5.  Orofacial herpes simplex virus infection in hairless mice: latent virus in trigeminal ganglia after topical antiviral treatment.

Authors:  R J Klein; A E Friedman-Kien; P B Yellin
Journal:  Infect Immun       Date:  1978-04       Impact factor: 3.441

6.  Protective effect of an oral infection with herpes simplex virus type 1 against subsequent genital infection with herpes simplex virus type 2.

Authors:  B Sturn; K E Schneweis
Journal:  Med Microbiol Immunol       Date:  1978-07-04       Impact factor: 3.402

7.  Herpes Simplex Virus 1 Replication, Ocular Disease, and Reactivations from Latency Are Restricted Unilaterally after Inoculation of Virus into the Lip.

Authors:  Nolwenn Poccardi; Antoine Rousseau; Oscar Haigh; Julie Takissian; Thierry Naas; Claire Deback; Louise Trouillaud; Mohammad Issa; Simon Roubille; Franceline Juillard; Stacey Efstathiou; Patrick Lomonte; Marc Labetoulle
Journal:  J Virol       Date:  2019-11-26       Impact factor: 5.103

8.  Pathogenetic mechansims of recurrent herpes simplex virus infections.

Authors:  R J Klein
Journal:  Arch Virol       Date:  1976       Impact factor: 2.574

9.  Pathogenesis of latent herpes simplex virus infection of the trigeminal ganglion in guinea pigs: effects of age, passive immunization, and hydrocortisone.

Authors:  R B Tenser; G D Hsiung
Journal:  Infect Immun       Date:  1977-04       Impact factor: 3.441

10.  Encephalitis resulting from reactivation of latent herpes simplex virus in mice.

Authors:  T Sekizawa; H Openshaw
Journal:  J Virol       Date:  1984-04       Impact factor: 5.103
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