Literature DB >> 16642537

Investigating nonribosomal peptide and polyketide biosynthesis by direct detection of intermediates on >70 kDa polypeptides by using Fourier-transform mass spectrometry.

Leslie M Hicks1, Matthew T Mazur, Leah M Miller, Pieter C Dorrestein, Nathan A Schnarr, Chaitan Khosla, Neil L Kelleher.   

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Year:  2006        PMID: 16642537     DOI: 10.1002/cbic.200500416

Source DB:  PubMed          Journal:  Chembiochem        ISSN: 1439-4227            Impact factor:   3.164


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  6 in total

1.  Time-resolved limited proteolysis of mitogen-activated protein kinase-activated protein kinase-2 determined by LC/MS only.

Authors:  Li Tao; Susan E Kiefer; Dianlin Xie; James W Bryson; Stanley A Hefta; Michael L Doyle
Journal:  J Am Soc Mass Spectrom       Date:  2008-03-18       Impact factor: 3.109

2.  A mechanism-based fluorescence transfer assay for examining ketosynthase selectivity.

Authors:  Gitanjeli Prasad; Lawrence S Borketey; Tsung-Yi Lin; Nathan A Schnarr
Journal:  Org Biomol Chem       Date:  2012-07-18       Impact factor: 3.876

3.  Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry.

Authors:  Pieter C Dorrestein; Stefanie B Bumpus; Christopher T Calderone; Sylvie Garneau-Tsodikova; Zachary D Aron; Paul D Straight; Roberto Kolter; Christopher T Walsh; Neil L Kelleher
Journal:  Biochemistry       Date:  2006-10-24       Impact factor: 3.162

4.  FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF.

Authors:  Michael J Meehan; Xinkai Xie; Xiling Zhao; Wei Xu; Yi Tang; Pieter C Dorrestein
Journal:  Biochemistry       Date:  2010-12-22       Impact factor: 3.162

Review 5.  Accessing natural product biosynthetic processes by mass spectrometry.

Authors:  Stefanie B Bumpus; Neil L Kelleher
Journal:  Curr Opin Chem Biol       Date:  2008-10       Impact factor: 8.822

6.  Stereospecificity of ketoreductase domains of the 6-deoxyerythronolide B synthase.

Authors:  Roselyne Castonguay; Weiguo He; Alice Y Chen; Chaitan Khosla; David E Cane
Journal:  J Am Chem Soc       Date:  2007-10-06       Impact factor: 15.419

  6 in total

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