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Literature DB >> 16642043

Bcl2 phosphorylation and active PKC alpha are associated with poor survival in AML.

S Kurinna, M Konopleva, S L Palla, W Chen, S Kornblau, R Contractor, X Deng, W S May, M Andreeff, P P Ruvolo.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2006 PMID： 16642043 DOI： 10.1038/sj.leu.2404248

Source DB: PubMed Journal: Leukemia ISSN： 0887-6924 Impact factor: 11.528

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Cited

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18 in total

1. Protein phosphatase 2A inactivates Bcl2's antiapoptotic function by dephosphorylation and up-regulation of Bcl2-p53 binding.

Authors: Xingming Deng; Fengqin Gao; W Stratford May
Journal: Blood Date: 2008-10-09 Impact factor: 22.113

2. Targeting PKC-mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid leukemia-derived cell lines and blast cells.

Authors: Peter P Ruvolo; Liran Zhou; Julie C Watt; Vivian R Ruvolo; Jared K Burks; Tilahun Jiffar; Steven Kornblau; Marina Konopleva; Michael Andreeff
Journal: J Cell Biochem Date: 2011-06 Impact factor: 4.429

Review 3. Inflammation and survival pathways: chronic lymphocytic leukemia as a model system.

Authors: Lisa S Chen; Kumudha Balakrishnan; Varsha Gandhi
Journal: Biochem Pharmacol Date: 2010-08-07 Impact factor: 5.858

4. Role for PKC δ in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells.

Authors: Vivian R Ruvolo; Kul B Karanjeet; Todd F Schuster; Rhoderick Brown; Yibin Deng; Edward Hinchcliffe; Peter P Ruvolo
Journal: J Signal Transduct Date: 2010-01-01

5. Primary cilia are present on human blood and bone marrow cells and mediate Hedgehog signaling.

Authors: Mohan Singh; Parvesh Chaudhry; Akil A Merchant
Journal: Exp Hematol Date: 2016-09-07 Impact factor: 3.084

6. Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8).

Authors: Monica L Guzman; Xiaojie Li; Cheryl A Corbett; Randall M Rossi; Timothy Bushnell; Jane L Liesveld; Josée Hébert; Fay Young; Craig T Jordan
Journal: Blood Date: 2007-09-04 Impact factor: 22.113

Bcl2 phosphorylation and active PKC alpha are associated with poor survival in AML.

1. Protein phosphatase 2A inactivates Bcl2's antiapoptotic function by dephosphorylation and up-regulation of Bcl2-p53 binding.

2. Targeting PKC-mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid leukemia-derived cell lines and blast cells.

Review 3. Inflammation and survival pathways: chronic lymphocytic leukemia as a model system.

4. Role for PKC δ in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells.

5. Primary cilia are present on human blood and bone marrow cells and mediate Hedgehog signaling.

6. Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8).

7. Nicotine, through upregulating pro-survival signaling, cooperates with NNK to promote transformation.

Review 8. The complexities of PKCα signaling in cancer.

9. Sensitization of epithelial growth factor receptors by nicotine exposure to promote breast cancer cell growth.

10. Sensitization of human pancreatic cancer cells harboring mutated K-ras to apoptosis.