Literature DB >> 16641765

Questionnaire survey of spine surgeons on the use of methylprednisolone for acute spinal cord injury.

Jason C Eck1, Dean Nachtigall, S Craig Humphreys, Scott D Hodges.   

Abstract

STUDY
DESIGN: A questionnaire survey.
OBJECTIVE: Estimate the use and justification of the steroid protocol for spinal cord injury (SCI) patients. SUMMARY OF BACKGROUND DATA: There remains significant debate over clinical benefits and potential complications of the steroid protocol for SCI patients.
METHODS: A survey was sent to spine surgeons requesting information on 1) specialization, 2) trauma center affiliation, 3) use of steroid protocol, 4) justification of using steroid protocol, and 5) SCI volume.
RESULTS: Responses were received from 305 surgeons. Fourteen (4.6%) surgeons used steroids only if initiated before their consult, 262 (85.9%) would initiate if within the accepted 8-hour timeframe, 20 (6.6%) did not use steroids at all, and 9 (3.0%) used a different protocol. Justification for steroids use: 65 improved recovery, 64 institutional protocol, 110 medicolegal reasons, and 26 did not personally initiate steroids. Eighteen surgeons listed both clinical benefit and institutional protocol, and 22 others listed both institutional protocol and medicolegal reasons.
CONCLUSIONS: The majority (90.5%) of responding surgeons used the steroid protocol; however, only 24.1% used the steroid protocol due to a belief in improved clinical outcomes.

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Year:  2006        PMID: 16641765     DOI: 10.1097/01.brs.0000214886.21265.8c

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  19 in total

1.  Moving beyond depression: Excessively closed science hurts.

Authors:  Fred H Geisler
Journal:  BMJ       Date:  2008-03-22

2.  Methyl Prednisolone in Spinal Cord Injury : Is the Sheen Fading?

Authors:  K I Mathai
Journal:  Med J Armed Forces India       Date:  2011-07-21

3.  Neuroprotective Effects of Direct Intrathecal Administration of Granulocyte Colony-Stimulating Factor in Rats with Spinal Cord Injury.

Authors:  Wu-Fu Chen; Chun-Hong Chen; Nan-Fu Chen; Chun-Sung Sung; Zhi-Hong Wen
Journal:  CNS Neurosci Ther       Date:  2015-07-20       Impact factor: 5.243

Review 4.  Cervical spine injuries in American football.

Authors:  Jeffrey A Rihn; David T Anderson; Kathleen Lamb; Peter F Deluca; Ahmed Bata; Paul A Marchetto; Nuno Neves; Alexander R Vaccaro
Journal:  Sports Med       Date:  2009       Impact factor: 11.136

5.  Current use of methylprednisolone for acute spinal cord injury in Poland: survey study.

Authors:  Grzegorz Miekisiak; Wojciech Kloc; Witold Janusz; Jacek Kaczmarczyk; Dariusz Latka; Daniel Zarzycki
Journal:  Eur J Orthop Surg Traumatol       Date:  2014-02-05

6.  Anesthetic considerations in acute spinal cord trauma.

Authors:  Neil Dooney; Armagan Dagal
Journal:  Int J Crit Illn Inj Sci       Date:  2011-01

Review 7.  Serine Proteases and Chemokines in Neurotrauma: New Targets for Immune Modulating Therapeutics in Spinal Cord Injury.

Authors:  Roxana N Beladi; Kyle S Varkoly; Lauren Schutz; Liqiang Zhang; Jordan R Yaron; Qiuyun Guo; Michelle Burgin; Ian Hogue; Wesley Tierney; Wojciech Dobrowski; Alexandra R Lucas
Journal:  Curr Neuropharmacol       Date:  2021       Impact factor: 7.708

8.  Effects of the combination of methylprednisolone with aminoguanidine on functional recovery in rats following spinal cord injury.

Authors:  Zongshu Li; Juan DU; Hongxia Sun; Jing Mang; Jinting He; Jiaoqi Wang; Hongyu Liu; Zhongxin Xu
Journal:  Exp Ther Med       Date:  2014-03-10       Impact factor: 2.447

9.  Management of thoracolumbar spine trauma: An overview.

Authors:  S Rajasekaran; Rishi Mugesh Kanna; Ajoy Prasad Shetty
Journal:  Indian J Orthop       Date:  2015 Jan-Feb       Impact factor: 1.251

10.  Mortality and morbidity after high-dose methylprednisolone treatment in patients with acute cervical spinal cord injury: a propensity-matched analysis using a nationwide administrative database.

Authors:  Hirotaka Chikuda; Hideo Yasunaga; Katsushi Takeshita; Hiromasa Horiguchi; Hiroshi Kawaguchi; Kazuhiko Ohe; Kiyohide Fushimi; Sakae Tanaka
Journal:  Emerg Med J       Date:  2013-02-28       Impact factor: 2.740

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