Complications in a consecutive series of 250 free flap operations.

The purpose of this study was to determine the rate of major and minor flap, donor site, and systemic complications in a consecutive series of 250 free flap operations. The following factors were analyzed to determine their significance on complication rates: age of patient, gender, wound etiology, smoking history, type of flap, operative time, vein graft use, surgeon experience, and the presence of comorbid disease. The major flap, donor-site, and systemic complication rates were 17.2%, 2%, and 6.4%, respectively. The minor flap, donor-site, and systemic complication rates were 7.2%, 12.8%, and 7.2%, respectively. The presence of comorbid medical condition was the only factor which had a statistically significant impact on the rate of major flap complications (P = 0.02). Age and comorbid disease impacted on major systemic complications (P = 0.04).