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Literature DB >> 16641461

Curcumin-artemisinin combination therapy for malaria.

Dalavaikodihalli Nanjaiah Nandakumar¹, Viswanathan Arun Nagaraj, Palakkod Govindan Vathsala, Pundi Rangarajan, Govindarajan Padmanaban.

Abstract

Artemisinin and curcumin show an additive interaction in killing Plasmodium falciparum in culture. In vivo, 3 oral doses of curcumin following a single injection of alpha,beta-arteether to Plasmodium berghei-infected mice are able to prevent recrudescence due to alpha,beta-arteether monotherapy and ensure almost 100% survival of the animals.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2006 PMID： 16641461 PMCID： PMC1472230 DOI： 10.1128/AAC.50.5.1859-1860.2006

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

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