Literature DB >> 16640518

Accidental transplantation of a kidney with a cystic renal cell carcinoma following living donation: management and 1 yr follow-up.

Michael Neipp1, Anke Schwarz, Stefanie Pertschy, Jürgen Klempnauer, Thomas Becker.   

Abstract

Transmission of cancer is a fatal risk in organ transplantation. We present a case of incidental renal carcinoma in a kidney obtained from a living donor. A 56-yr-old father was evaluated for donation for his 28-yr-old daughter. An MRT scan revealed two cysts in the right kidney. Right-sided donor nephrectomy and subsequent transplantation was performed. The wall of the prominent cyst was partially excised prior to transplantation. Histology revealed a high-grade renal clear cell carcinoma 10 d after transplantation. Following careful evaluation the recipient underwent partial nephrectomy. Immunosuppression was switched to rapamune. The graft function remained stable. Donor and recipient are without evidence of tumor recurrence 1 yr after transplantation. Our policy to obtain the kidney presenting anatomical variations proved to be beneficial for the donor. In case of transmission of cancer partial resection preserving graft function might be justified.

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Year:  2006        PMID: 16640518     DOI: 10.1111/j.1399-0012.2005.00455.x

Source DB:  PubMed          Journal:  Clin Transplant        ISSN: 0902-0063            Impact factor:   2.863


  5 in total

Review 1.  Donor transmitted and de novo cancer after liver transplantation.

Authors:  Rajeev Desai; James Neuberger
Journal:  World J Gastroenterol       Date:  2014-05-28       Impact factor: 5.742

2.  Detection and management of renal cell carcinoma in the renal allograft.

Authors:  Gyula Végső; Éva Toronyi; Pál Ákos Deák; Attila Doros; Róbert Miklós Langer
Journal:  Int Urol Nephrol       Date:  2012-09-01       Impact factor: 2.370

3.  Renal transplantation with kidneys affected by tumours.

Authors:  Muhammad Arslan Khurram; Aliu Oladipupo Sanni; David Rix; David Talbot
Journal:  Int J Nephrol       Date:  2011-01-18

Review 4.  Renal Cancer in Recipients of Kidney Transplant.

Authors:  Prajwal Dhakal; Smith Giri; Krishmita Siwakoti; Supratik Rayamajhi; Vijaya Raj Bhatt
Journal:  Rare Tumors       Date:  2017-03-24

5.  Experiences of renal transplants from donors with renal cell carcinoma after ex vivo partial nephrectomy.

Authors:  Sung Yoon Lim; Myung Gyu Kim; Kwon Tae Park; Cheol Woong Jung
Journal:  Ann Surg Treat Res       Date:  2017-04-27       Impact factor: 1.859

  5 in total

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