OBJECTIVE: The case report suggests the indispensability of preoperative accurate psychiatric checkups especially in temporal resections. METHOD: A single case was reported. RESULTS: We report the case of a 20-year-old woman suffering for 12 years from primary generalized epilepsy, attributed to left-sided hippocampal sclerosis. Because seizures were resistant to drug therapy, she underwent amygdala-hippocampectomy at the age of 18. Furthermore, she had previously been victim of childhood sexual abuse. Two weeks after epilepsy surgery, she manifested symptoms of post-traumatic stress disorder (PTSD). CONCLUSION: There is evidence that the amygdala-hippocampal region is both functionally and morphologically involved in the aetiology of PTSD. The removal of this marked neuroanatomical region and the resulting disconnection and asymmetry between right and left amygdala-hippocampal region might be seen as an evidence for this region aetiologically being involved in the patient's PTSD symptoms.
OBJECTIVE: The case report suggests the indispensability of preoperative accurate psychiatric checkups especially in temporal resections. METHOD: A single case was reported. RESULTS: We report the case of a 20-year-old woman suffering for 12 years from primary generalized epilepsy, attributed to left-sided hippocampal sclerosis. Because seizures were resistant to drug therapy, she underwent amygdala-hippocampectomy at the age of 18. Furthermore, she had previously been victim of childhood sexual abuse. Two weeks after epilepsy surgery, she manifested symptoms of post-traumatic stress disorder (PTSD). CONCLUSION: There is evidence that the amygdala-hippocampal region is both functionally and morphologically involved in the aetiology of PTSD. The removal of this marked neuroanatomical region and the resulting disconnection and asymmetry between right and left amygdala-hippocampal region might be seen as an evidence for this region aetiologically being involved in the patient's PTSD symptoms.
Authors: Kelly R Bijanki; Sanne J H van Rooij; Timothy D Ely; Jennifer S Stevens; Cory S Inman; Rebecca E Fasano; Sierra E Carter; Sterling J Winters; Justin R Baman; Daniel L Drane; Tanja Jovanovic; Jon T Willie Journal: Neurosurgery Date: 2020-09-15 Impact factor: 4.654
Authors: Lucas Canto-de-Souza; Peyton G Demetrovich; Samantha Plas; Rimenez R Souza; Joseph Epperson; Krista L Wahlstrom; Ricardo Luiz Nunes-de-Souza; Ryan T LaLumiere; Cleopatra Silva Planeta; Christa K McIntyre Journal: Front Behav Neurosci Date: 2021-12-20 Impact factor: 3.617
Authors: Antoine Yrondi; Luc Valton; Viviane Bouilleret; Nozar Aghakhani; Jonathan Curot; Philippe Jean Birmes Journal: Front Psychiatry Date: 2020-04-28 Impact factor: 4.157