S E Monstad1, C A Vedeler. 1. Department of Neurology, Haukeland University Hospital; Department of Clinical Medicine, University of Bergen, Norway. sissel.monstad@helse_bergen.no
Abstract
INTRODUCTION: Onconeural antibodies are found in some patients with cancer, and are associated with paraneoplastic neurological syndromes. METHOD: A multi-well adapted fluid-phase immunoassay using radiolabelled recombinant onconeural proteins for the detection of onconeural antibodies is described. RESULT AND CONCLUSION: This immunoprecipitation technique is more sensitive in detecting onconeural antibodies than immunohistochemistry and immune blots.
INTRODUCTION: Onconeural antibodies are found in some patients with cancer, and are associated with paraneoplastic neurological syndromes. METHOD: A multi-well adapted fluid-phase immunoassay using radiolabelled recombinant onconeural proteins for the detection of onconeural antibodies is described. RESULT AND CONCLUSION: This immunoprecipitation technique is more sensitive in detecting onconeural antibodies than immunohistochemistry and immune blots.