Literature DB >> 16637932

Multiplexed phosphoprotein analysis in immune cells.

S Gavasso1, K-M Myhr, C Vedeler.   

Abstract

Analyzing signaling networks in immune cells is of particular interests in diseases where treatment choices are preferentially immunomodulatory. By combining phospho-specific antibodies with multicolor flow cytometry it is possible to perform quantitative multiparameter analysis of signaling pathways within complex cell populations. Multiplexed phosphoprotein analysis will potentially incorporate environmental factors such as toxins or pathogens and genetic variability of individual patients in a step towards personalized medicine.

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Year:  2006        PMID: 16637932     DOI: 10.1111/j.1600-0404.2006.00618.x

Source DB:  PubMed          Journal:  Acta Neurol Scand Suppl        ISSN: 0065-1427


  1 in total

1.  Deficient phosphorylation of Stat1 in leukocytes identifies neutralizing antibodies in multiple sclerosis patients treated with interferon-beta.

Authors:  Sonia Gavasso; Ellen Faergestad Mosleth; Tove Marøy; Katarina Jørgensen; Hanne-Linda Nakkestad; Bjørn-Tore Gjertsen; Kjell-Morten Myhr; Christian Vedeler
Journal:  PLoS One       Date:  2014-02-19       Impact factor: 3.240

  1 in total

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