Literature DB >> 1663719

Hepatitis B virus e antigen and primary hepatocellular carcinoma.

T M Lin1, C J Chen, S N Lu, A S Chang, Y C Chang, S T Hsu, J Y Liu, Y F Liaw, W Y Chang.   

Abstract

Serum samples from 243 cases of primary hepatocellular carcinoma (PHC) and 302 non-PHC hospital controls were tested for hepatitis B virus (HBV) surface antigen (HBsAg), antibody to HBsAg (anti-HBs), antibody to HBV core antigen (anti-HBc), HBV e antigen (HBeAg) and antibody to HBeAg (anti-HBe) with radioimmunoassays using commercial kits. A total of 236 (97%) PHC cases and 302 (100%) hospital controls were positive for one or more HBV markers. While 188 (77%) PHC cases and 57 (19%) controls were positive for HBsAg, 44 (18%) PHC cases and 5 (2%) controls were positive for both BHsAg and HBeAg. Statistically significant associations with PHC were observed for HBsAg and HBeAg with an odds ratio (OR) of 10.0 and 3.2, respectively, when age, sex and other markers were adjusted. The stratification analysis of interactive effects of HBV infection markers on the development of PHC showed that HBeAg carrier status may increase PHC risk associated with HBsAg status.

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Year:  1991        PMID： 1663719

Source DB:  PubMed          Journal:  Anticancer Res        ISSN： 0250-7005            Impact factor:   2.480


  7 in total

1.  Effect of the presence of hepatitis B e antigen on prognosis after liver resection for hepatocellular carcinoma in patients with chronic hepatitis B.

Authors:  Shoji Kubo; Kazuhiro Hirohashi; Osamu Yamazaki; Mitsuharu Matsuyama; Hiromu Tanaka; Katsuhiko Horii; Taichi Shuto; Takatsugu Yamamoto; Shuichi Kawai; Kenichi Wakasa; Shuhei Nishiguchi; Hiroaki Kinoshita
Journal:  World J Surg       Date:  2002-02-19       Impact factor: 3.352

2.  Chronic hepatitis B carriers with null genotypes of glutathione S-transferase M1 and T1 polymorphisms who are exposed to aflatoxin are at increased risk of hepatocellular carcinoma.

Authors:  C J Chen; M W Yu; Y F Liaw; L W Wang; S Chiamprasert; F Matin; A Hirvonen; D A Bell; R M Santella
Journal:  Am J Hum Genet       Date:  1996-07       Impact factor: 11.025

3.  Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma.

Authors:  Masao Omata; Laurentius A Lesmana; Ryosuke Tateishi; Pei-Jer Chen; Shi-Ming Lin; Haruhiko Yoshida; Masatoshi Kudo; Jeong Min Lee; Byung Ihn Choi; Ronnie T P Poon; Shuichiro Shiina; Ann Lii Cheng; Ji-Dong Jia; Shuntaro Obi; Kwang Hyub Han; Wasim Jafri; Pierce Chow; Seng Gee Lim; Yogesh K Chawla; Unggul Budihusodo; Rino A Gani; C Rinaldi Lesmana; Terawan Agus Putranto; Yun Fan Liaw; Shiv Kumar Sarin
Journal:  Hepatol Int       Date:  2010-03-18       Impact factor: 6.047

Review 4.  Significance of viral status on occurrence of hepatitis B-related hepatocellular carcinoma.

Authors:  Li-Shuai Qu; Guo-Xiong Zhou
Journal:  World J Gastroenterol       Date:  2014-05-28       Impact factor: 5.742

5.  Epidemiology and Prevention of Hepatitis B Virus Infection.

Authors:  Jinlin Hou; Zhihua Liu; Fan Gu
Journal:  Int J Med Sci       Date:  2005-01-05       Impact factor: 3.738

6.  Additive effect modification of hepatitis B surface antigen and e antigen on the development of hepatocellular carcinoma.

Authors:  J F Tsai; J E Jeng; M S Ho; W Y Chang; M Y Hsieh; Z Y Lin; J H Tsai
Journal:  Br J Cancer       Date:  1996-06       Impact factor: 7.640

7.  Wisteria floribunda agglutinin-positive Mac-2-binding protein in the prediction of disease severity in chronic hepatitis B patients.

Authors:  Ming-Lun Yeh; Chung-Feng Huang; Ching-I Huang; Chia-Yen Dai; I-Hung Lin; Po-Cheng Liang; Meng-Hsuan Hsieh; Zu-Yau Lin; Shinn-Chern Chen; Jee-Fu Huang; Jyh-Jou Chen; Ming-Lung Yu; Wan-Long Chuang
Journal:  PLoS One       Date:  2019-08-08       Impact factor: 3.240
  7 in total

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