Literature DB >> 16636880

The incidence, timing, and predisposing factors of germinal matrix and intraventricular hemorrhage (GMH/IVH) in preterm neonates.

Hassan Kadri1, Alhakam A Mawla, Jehad Kazah.   

Abstract

BACKGROUND: Germinal matrix and intraventricular hemorrhage (GMH/IVH) is a known complication occurring in the first week of life in preterm neonates. However, the precise time of its occurrence and the ideal time to perform diagnostic imaging studies remain controversial. The purpose of this paper is to address these two issues in our patient population to allocate our resources to those at highest risk.
MATERIALS AND METHODS: This study included 282 premature newborns (under 37 weeks of gestation) that were admitted to our neonate ICU in a year's time and screened for GMH/IVH. They were grouped in four categories according to their weight at birth, and according to their gestational age. All patients had a daily cranial ultrasound during the first week. It was then repeated once in the second week and once in the third.
RESULTS: We found that the incidence of GMH/IVH among preterm neonates was 44.68%. It was inversely related to the weight and the age of the newborn. The onset of bleeding coordinated with the occurrence of hypoxia and respiratory distress requiring mechanical ventilation. The majorities occurred in the first 7 days of life; they were mostly grade I and II according to the Papule classification and silent for the most part. Complications were present in 41% of the survivors.

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Year:  2006        PMID: 16636880     DOI: 10.1007/s00381-006-0050-6

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  39 in total

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  32 in total

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2.  Outcome of ventriculoperitoneal shunt and predictors of shunt revision in infants with posthemorrhagic hydrocephalus.

Authors:  Shyamal C Bir; Subhas Konar; Tanmoy Kumar Maiti; Piyush Kalakoti; Papireddy Bollam; Anil Nanda
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3.  A novel preclinical model of germinal matrix hemorrhage using neonatal rats.

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4.  Neuroprotection by melatonin after germinal matrix hemorrhage in neonatal rats.

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Journal:  Acta Neurochir Suppl       Date:  2011

5.  Incidence of brain injuries in premature infants with gestational age ≤ 34 weeks in ten urban hospitals in China.

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6.  Incidence of hydrocephalus and the need to ventriculoperitoneal shunting in premature infants with intraventricular hemorrhage: risk factors and outcome.

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9.  Indomethacin prophylaxis to prevent intraventricular hemorrhage: association between incidence and timing of drug administration.

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10.  PPARγ-induced upregulation of CD36 enhances hematoma resolution and attenuates long-term neurological deficits after germinal matrix hemorrhage in neonatal rats.

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