Literature DB >> 16636252

Magnetic source imaging localizes epileptogenic zone in children with tuberous sclerosis complex.

J Y Wu1, W W Sutherling, S Koh, N Salamon, R Jonas, S Yudovin, R Sankar, W D Shields, G W Mathern.   

Abstract

The authors assessed whether magnetoencephalography/magnetic source imaging (MEG/MSI) identified epileptogenic zones in patients with tuberous sclerosis complex (TSC). In six TSC children with focal seizures, ictal video-EEG predicted the region of resection with 56% sensitivity, 80% specificity, and 77% accuracy (p = 0.02), whereas interictal MEG/MSI fared better (100%, 94%, and 95%, respectively; p < 0.0001). Interictal MEG/MSI seems to identify epileptogenic zones more accurately in children with TSC and focal intractable epilepsy.

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Year:  2006        PMID： 16636252     DOI： 10.1212/01.wnl.0000208412.59491.9b

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  21 in total

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Review 4.  Epilepsy secondary to tuberous sclerosis: lessons learned and current challenges.

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5.  Influence of magnetic source imaging for planning intracranial EEG in epilepsy.

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6.  Paroxysmal fast activity: an interictal scalp EEG marker of epileptogenesis in children.

Authors:  Joyce Y Wu; Susan Koh; Raman Sankar; Gary W Mathern
Journal:  Epilepsy Res       Date:  2008-09-19       Impact factor: 3.045

7.  Factors associated with failed focal neocortical epilepsy surgery.

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8.  Improved outcomes in pediatric epilepsy surgery: the UCLA experience, 1986-2008.

Authors:  M Hemb; T R Velasco; M S Parnes; J Y Wu; J T Lerner; J H Matsumoto; S Yudovin; W D Shields; R Sankar; N Salamon; H V Vinters; G W Mathern
Journal:  Neurology       Date:  2010-04-28       Impact factor: 9.910

9.  Hippocampal abnormalities in an MR imaging series of patients with tuberous sclerosis.

Authors:  H P P Gama; A J da Rocha; R M F Valério; C J da Silva; L A L Garcia
Journal:  AJNR Am J Neuroradiol       Date:  2010-01-06       Impact factor: 3.825

10.  Decreased language laterality in tuberous sclerosis complex: a relationship between language dominance and tuber location as well as history of epilepsy.

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