| Literature DB >> 16636247 |
A B Ragin1, Y Wu, P Storey, B A Cohen, R R Edelman, L G Epstein.
Abstract
Various biomarkers have been suggested as associative or predictive of HIV-associated neurocognitive impairment. Plasma levels of monocyte chemoattractant protein 1 (MCP-1), tumor necrosis factor alpha (TNF-alpha), and hematocrit were evaluated for relationships with diffusion tensor imaging measurements of centrum semiovale, caudate, and putamen. MCP-1 levels correlated with tissue status (mean diffusivity) in all examined regions. Plasma markers were also significantly correlated with anisotropy measurements in centrum semiovale (TNF-alpha) and putamen (hematocrit).Entities:
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Year: 2006 PMID: 16636247 PMCID: PMC2367223 DOI: 10.1212/01.wnl.0000208433.34723.65
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910