Literature DB >> 16635673

A pilot trial of treprostinil for the treatment and prevention of digital ulcers in patients with systemic sclerosis.

Lorinda Chung1, David Fiorentino.   

Abstract

We performed a pilot trial of subcutaneous treprostinil for the treatment of digital ulcers in scleroderma. Of the 5 patients completing therapy, ulcer size significantly decreased and no new ulcers occurred on continuous therapy. Although effective, the high rate of injection site reactions may limit the utility of this therapy.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 16635673     DOI: 10.1016/j.jaad.2006.02.004

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  13 in total

Review 1.  Recent advances on pathogenesis and therapies in systemic sclerosis.

Authors:  Norihito Yazawa; Manabu Fujimoto; Kunihiko Tamaki
Journal:  Clin Rev Allergy Immunol       Date:  2007-10       Impact factor: 8.667

2.  Calcinosis is associated with digital ischaemia in systemic sclerosis-a longitudinal study.

Authors:  Murray Baron; Janet Pope; David Robinson; Niall Jones; Nader Khalidi; Peter Docherty; Elzbieta Kaminska; Ariel Masetto; Evelyn Sutton; Jean-Pierre Mathieu; Sophie Ligier; Tamara Grodzicky; Sharon LeClercq; Carter Thorne; Geneviève Gyger; Douglas Smith; Paul R Fortin; Maggie Larché; Maysan Abu-Hakima; Tatiana S Rodriguez-Reyna; Antonio R Cabral-Castaneda; Marvin J Fritzler; Mianbo Wang; Marie Hudson
Journal:  Rheumatology (Oxford)       Date:  2016-09-04       Impact factor: 7.580

3.  Management of Raynaud's Phenomenon in the Patient with Connective Tissue Disease.

Authors:  Soumya Chatterjee
Journal:  Curr Treat Options Cardiovasc Med       Date:  2010-04

Review 4.  Dissecting fibrosis: therapeutic insights from the small-molecule toolbox.

Authors:  Carmel B Nanthakumar; Richard J D Hatley; Seble Lemma; Jack Gauldie; Richard P Marshall; Simon J F Macdonald
Journal:  Nat Rev Drug Discov       Date:  2015-09-04       Impact factor: 84.694

Review 5.  Points to consider for skin ulcers in systemic sclerosis.

Authors:  Felice Galluccio; Yannick Allanore; Lázló Czirjak; Daniel E Furst; Dinesh Khanna; Marco Matucci-Cerinic
Journal:  Rheumatology (Oxford)       Date:  2017-09-01       Impact factor: 7.580

6.  Raynaud's phenomenon and digital ischemia: a practical approach to risk stratification, diagnosis and management.

Authors:  Zsuzsanna H McMahan; Fredrick M Wigley
Journal:  Int J Clin Rheumtol       Date:  2010

Review 7.  Vascular disease in scleroderma.

Authors:  Fredrick M Wigley
Journal:  Clin Rev Allergy Immunol       Date:  2009-06       Impact factor: 8.667

8.  Digital ischemia in scleroderma spectrum of diseases.

Authors:  Elena Schiopu; Ann J Impens; Kristine Phillips
Journal:  Int J Rheumatol       Date:  2010-08-31

9.  Endothelin Receptor Antagonists for the Treatment of Raynaud's Phenomenon and Digital Ulcers in Systemic Sclerosis.

Authors:  Kait Arefiev; David F Fiorentino; Lorinda Chung
Journal:  Int J Rheumatol       Date:  2011-10-27

10.  Locoregional Treatments for Digital Ulcers in Systemic Sclerosis: A Systematic Review.

Authors:  Ingrid Costedoat; Maeva Masson; Thomas Barnetche; Pierre Duffau; Estibaliz Lazaro; Christophe Richez; Julien Seneschal; Marie-Elise Truchetet
Journal:  Acta Derm Venereol       Date:  2021-06-22       Impact factor: 3.875

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.