| Literature DB >> 16635604 |
Tomomi Koizumi1, Masaki Yokoyama, Susumu Namikawa, Nehiro Kuriyama, Mizuo Nameki, Takashi Nakayama, Hideaki Kaneda, Krishnankutty Sudhir, Paul G Yock, Nobuyuki Komiyama, Peter J Fitzgerald.
Abstract
This study examined whether coronary focal vasospasm occurs in a nonuniform distribution within the coronary tree and whether a longitudinal plaque distribution pattern is present in patients with vasospastic angina using 3-dimensional intravascular ultrasound analysis. Of 121 patients with clinically suspected angina without fixed stenosis in the coronary arteries, vasospasm was provoked in 82 patients with 92 lesions (42 focal, 50 diffuse) by intravenous ergonovine maleate injection. Most focal vasospasms occurred in the proximal third of the coronary arteries (proximal 28, mid 8, distal 6, p <0.01), corresponding to the historical high-risk zones for acute coronary occlusion. More plaque burden also existed in the proximal third of the coronary arteries in patients with focal vasospasm.Entities:
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Year: 2006 PMID： 16635604 DOI： 10.1016/j.amjcard.2005.11.073
Source DB: PubMed Journal: Am J Cardiol ISSN： 0002-9149 Impact factor: 2.778