Literature DB >> 16635586

A tale of three genomes: the kinetoplastids have arrived.

Jessica C Kissinger1.   

Abstract

July 2005 marked a milestone in kinetoplastid biology research. A tour de force effort led by the Tri-Trypanosomatidae "Tritryp" genome consortium yielded the publication of three prominent kinetoplastid parasite genome sequences: Trypanosoma brucei, Trypanosoma cruzi and Leishmania major. The individual and combined comparative analyses of these three genome sequences, combined with proteomic analyses, have yielded insights into topics ranging from genome evolution and horizontal gene transfer to potential new therapeutic and vaccine targets.

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Year:  2006        PMID: 16635586     DOI: 10.1016/j.pt.2006.04.002

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN: 1471-4922


  12 in total

Review 1.  Host-parasite interactions in trypanosomiasis: on the way to an antidisease strategy.

Authors:  Nicolas Antoine-Moussiaux; Philippe Büscher; Daniel Desmecht
Journal:  Infect Immun       Date:  2009-01-21       Impact factor: 3.441

2.  Designed compounds for recognition of 10 base pairs of DNA with two at binding sites.

Authors:  Yang Liu; Yun Chai; Arvind Kumar; Richard R Tidwell; David W Boykin; W David Wilson
Journal:  J Am Chem Soc       Date:  2012-03-09       Impact factor: 15.419

Review 3.  Multigene families in Trypanosoma cruzi and their role in infectivity.

Authors:  Luis Miguel De Pablos; Antonio Osuna
Journal:  Infect Immun       Date:  2012-03-19       Impact factor: 3.441

4.  Transcript Abundance of Putative Lipid Phosphate Phosphatases During Development of Trypanosoma brucei in the Tsetse Fly.

Authors:  Thiago Luiz Alves e Silva; Amy F Savage; Serap Aksoy
Journal:  Am J Trop Med Hyg       Date:  2016-02-08       Impact factor: 2.345

5.  Proteomic analysis of detergent-solubilized membrane proteins from insect-developmental forms of Trypanosoma cruzi.

Authors:  Esteban M Cordero; Ernesto S Nakayasu; Luciana G Gentil; Nobuko Yoshida; Igor C Almeida; José Franco da Silveira
Journal:  J Proteome Res       Date:  2009-07       Impact factor: 4.466

6.  Drug development to protozoan diseases.

Authors:  Lianet Monzote; Afshan Siddiq
Journal:  Open Med Chem J       Date:  2011-03-09

7.  Studies on the CPA cysteine peptidase in the Leishmania infantum genome strain JPCM5.

Authors:  Hubert Denise; Jacqueline Poot; Maribel Jiménez; Audrey Ambit; Daland C Herrmann; Arno N Vermeulen; Graham H Coombs; Jeremy C Mottram
Journal:  BMC Mol Biol       Date:  2006-11-13       Impact factor: 2.946

8.  Telomeric co-localization of the modified base J and contingency genes in the protozoan parasite Trypanosoma cruzi.

Authors:  Dilrukshi K Ekanayake; Michael J Cipriano; Robert Sabatini
Journal:  Nucleic Acids Res       Date:  2007-09-18       Impact factor: 16.971

9.  A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases.

Authors:  Ariel José Berenstein; María Paula Magariños; Ariel Chernomoretz; Fernán Agüero
Journal:  PLoS Negl Trop Dis       Date:  2016-01-06

Review 10.  Checks and balances? DNA replication and the cell cycle in Plasmodium.

Authors:  Holly Matthews; Craig W Duffy; Catherine J Merrick
Journal:  Parasit Vectors       Date:  2018-03-27       Impact factor: 3.876

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