OBJECTIVES: The aim of this study was to provide reference values for nasal bone length (NBL) scanned at 11-14 weeks' gestation in the Korean population and compare these values with those of the Caucasian and African-American populations. METHODS: From April 2004 to July 2004, fetal NBLs were measured in well-dated, non-anomalous fetuses at 11-14 weeks' gestation in the Korean population. Regression analysis was used to assess the relationship between NBL and crown-rump length (CRL), and reference values including the 5th, 50th, and 95th percentile were calculated for each gestational age. The reference values in our study were compared with those of the Caucasian and African-American populations. RESULTS: A total of 982 cases were prospectively included in the study. NBL increased linearly with advance in CRL and was described by the equation; NBL (mm) = 0.433 + 0.022 x CRL (mm), R(2) = 0.37. The median values (5%, 95%) were 1.5 mm (1.2 mm, 1.9 mm), 1.7 mm (1.4 mm, 2.1 mm), 1.9 mm (1.6 mm, 2.3 mm), and 2.1 mm (1.7 mm, 2.6 mm) for 11, 12, 13, and 14 weeks' gestation, respectively. The median values for each gestational age in the Korean population were significantly lower than those in the Caucasian and African-American populations (P < 0.0001). CONCLUSION: There is a difference in NBL scanned at 11-14 weeks' gestation between the Korean and the Caucasian/African-American populations, and so racial adjustment is needed in the evaluation of the fetal nasal bone for current first-trimester screening. Copyright 2006 John Wiley & Sons, Ltd.
OBJECTIVES: The aim of this study was to provide reference values for nasal bone length (NBL) scanned at 11-14 weeks' gestation in the Korean population and compare these values with those of the Caucasian and African-American populations. METHODS: From April 2004 to July 2004, fetal NBLs were measured in well-dated, non-anomalous fetuses at 11-14 weeks' gestation in the Korean population. Regression analysis was used to assess the relationship between NBL and crown-rump length (CRL), and reference values including the 5th, 50th, and 95th percentile were calculated for each gestational age. The reference values in our study were compared with those of the Caucasian and African-American populations. RESULTS: A total of 982 cases were prospectively included in the study. NBL increased linearly with advance in CRL and was described by the equation; NBL (mm) = 0.433 + 0.022 x CRL (mm), R(2) = 0.37. The median values (5%, 95%) were 1.5 mm (1.2 mm, 1.9 mm), 1.7 mm (1.4 mm, 2.1 mm), 1.9 mm (1.6 mm, 2.3 mm), and 2.1 mm (1.7 mm, 2.6 mm) for 11, 12, 13, and 14 weeks' gestation, respectively. The median values for each gestational age in the Korean population were significantly lower than those in the Caucasian and African-American populations (P < 0.0001). CONCLUSION: There is a difference in NBL scanned at 11-14 weeks' gestation between the Korean and the Caucasian/African-American populations, and so racial adjustment is needed in the evaluation of the fetal nasal bone for current first-trimester screening. Copyright 2006 John Wiley & Sons, Ltd.
Authors: Min Hoan Moon; Jeong Yeon Cho; Ju Hee Kim; Young Ho Lee; Sung Il Jung; Myung Sook Lee; Hyeun Cha Cho Journal: Korean J Radiol Date: 2008 Jan-Feb Impact factor: 3.500
Authors: Soo-Young Oh; Joon Seok Hong; Hyun-Joo Seol; Han Sung Hwang; Hyun Soo Park; Kunwoo Kim; Hyun Sun Ko; Dong-Wook Kwak; Moon Young Kim; Mi Hye Park; Min Jeong Oh; Joong Shin Park; Sa Jin Kim Journal: Obstet Gynecol Sci Date: 2015-01-16