Literature DB >> 1663393

Toxicity of hydroxyapatite in vitro: the effect of particle size.

E J Evans1.   

Abstract

Finely ground powders of synthetic hydroxyapatite applied to fibroblasts in vitro reduced the total growth rate and mitotic rate of the cells and increased the number of pycnotic cells. The effect was dose related and only occurred with small particles. The small particles appear to either adhere to the cells or are phagocytosed by them and the toxic effect may be physical rather than chemical.

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Year:  1991        PMID： 1663393     DOI： 10.1016/0142-9612(91)90054-e

Source DB:  PubMed          Journal:  Biomaterials        ISSN： 0142-9612            Impact factor:   12.479


  9 in total

1.  Osteoblast response to zirconia-hybridized pyrophosphate-stabilized amorphous calcium phosphate.

Authors:  Bryce M Whited; Drago Skrtic; Brian J Love; Aaron S Goldstein
Journal:  J Biomed Mater Res A       Date:  2006-03-01       Impact factor: 4.396

Review 2.  On the fate of particles liberated from hydroxyapatite coatings in vivo.

Authors:  C F Dunne; J Gibbons; D P FitzPatrick; K J Mulhall; K T Stanton
Journal:  Ir J Med Sci       Date:  2015-01-10       Impact factor: 1.568

3.  The effect of MgO on the solubility behavior and cell proliferation in a quaternary soluble phosphate based glass system.

Authors:  K Franks; V Salih; J C Knowles; I Olsen
Journal:  J Mater Sci Mater Med       Date:  2002-06       Impact factor: 3.896

4.  Viscoelastic properties of composites of calcium alginate and hydroxyapatite.

Authors:  I Wands; D E T Shepherd; D W L Hukins
Journal:  J Mater Sci Mater Med       Date:  2008-01-16       Impact factor: 3.896

5.  Small-sized granules of biphasic bone substitutes support fast implant bed vascularization.

Authors:  M Barbeck; M Dard; M Kokkinopoulou; J Markl; P Booms; R A Sader; C J Kirkpatrick; S Ghanaati
Journal:  Biomatter       Date:  2015

6.  Thin Degradable Coatings for Optimization of Osteointegration Associated with Simultaneous Infection Prophylaxis.

Authors:  Sophie Burtscher; Peter Krieg; Andreas Killinger; Ali Al-Ahmad; Michael Seidenstücker; Sergio Hernandez Latorre; Anke Bernstein
Journal:  Materials (Basel)       Date:  2019-10-25       Impact factor: 3.623

7.  The effect of particle size on the osteointegration of injectable silicate-substituted calcium phosphate bone substitute materials.

Authors:  Melanie J Coathup; Qian Cai; Charlie Campion; Thomas Buckland; Gordon W Blunn
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2013-01-30       Impact factor: 3.368

8.  Calcium Phosphate Bone Cements Including Sugar Surfactants: Part Two-Injectability, Adhesive Properties and Biocompatibility.

Authors:  Ariane Bercier; Stéphane Gonçalves; Helène Autefage; Fabienne Briand-Mesange; Olivier Lignon; Juliette Fitremann
Journal:  Materials (Basel)       Date:  2010-12-02       Impact factor: 3.623

9.  Influence of spray-dried hydroxyapatite-5-fluorouracil granules on cell lines derived from tissues of mesenchymal origin.

Authors:  Tim Scharnweber; Catarina Santos; Ralf-Peter Franke; Maria Margarida Almeida; Maria Elisabete V Costa
Journal:  Molecules       Date:  2008-11-01       Impact factor: 4.411
  9 in total

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