PURPOSE: To evaluate the ultrastructure of the cornea of Avellino corneal dystrophy (ACD) exacerbated by LASIK. METHODS: Three ACD patients with exacerbation of granular corneal deposits after LASIK underwent surgical removal of the corneal flap. The corneal flap was processed for scanning electron microscopy (SEM). RESULTS: SEM of all patients showed abnormal granular clusters in the fibrils of the corneal flap. CONCLUSION: Laser in situ keratomileusis induces corneal collagen abnormalities and adhesions of granular material in ACD patients.
PURPOSE: To evaluate the ultrastructure of the cornea of Avellino corneal dystrophy (ACD) exacerbated by LASIK. METHODS: Three ACDpatients with exacerbation of granular corneal deposits after LASIK underwent surgical removal of the corneal flap. The corneal flap was processed for scanning electron microscopy (SEM). RESULTS: SEM of all patients showed abnormal granular clusters in the fibrils of the corneal flap. CONCLUSION: Laser in situ keratomileusis induces corneal collagen abnormalities and adhesions of granular material in ACDpatients.
Authors: Shady T Awwad; Mario A Di Pascuale; Robert N Hogan; Stephan L Forstot; James P McCulley; Harrison D Cavanagh Journal: Am J Ophthalmol Date: 2008-02-19 Impact factor: 5.258
Authors: Jayne S Weiss; H U Møller; Walter Lisch; Shigeru Kinoshita; Anthony J Aldave; Michael W Belin; Tero Kivelä; Massimo Busin; Francis L Munier; Berthold Seitz; John Sutphin; Cecilie Bredrup; Mark J Mannis; Christopher J Rapuano; Gabriel Van Rij; Eung Kweon Kim; Gordon K Klintworth Journal: Cornea Date: 2008-12 Impact factor: 2.651