Literature DB >> 16630809

When a motor goes bad: a kinesin regulates neuronal survival.

David R Kaplan1, Freda D Miller.   

Abstract

In this issue of Cell, Midorikawa et al. (2006) demonstrate that the kinesin superfamily member KIF4, a microtubule-based molecular motor, regulates the survival of electrically active neurons in the developing brain by modulating the function of poly(ADP-ribose) polymerase-1 in an unexpected way.

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Year:  2006        PMID: 16630809     DOI: 10.1016/j.cell.2006.03.031

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  2 in total

1.  Overexpression of chromokinesin KIF4 inhibits proliferation of human gastric carcinoma cells both in vitro and in vivo.

Authors:  Jie Gao; Ningning Sai; Chengqin Wang; Xiehuang Sheng; Qianqian Shao; Chengjun Zhou; Yanqiu Shi; Shanzhen Sun; Xun Qu; Changjun Zhu
Journal:  Tumour Biol       Date:  2010-08-14

2.  The neuropeptide NAP provides neuroprotection against retinal ganglion cell damage after retinal ischemia and optic nerve crush.

Authors:  T Jehle; C Dimitriu; S Auer; R Knoth; M Vidal-Sanz; I Gozes; W A Lagrèze
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-04-15       Impact factor: 3.117

  2 in total

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