Literature DB >> 16630219

Aspergillus brain abscess in a patient with acute myeloid leukaemia successfully treated with voriconazole.

F Wandroo1, P Stableforth, Y Hasan.   

Abstract

Cerebral aspergillosis is associated with very high mortality in immunocompromised hosts. Conventional antifungal agents like amphotericin-B and itraconazole are almost ineffective in cerebral aspergillosis. Newer azoles have been shown to penetrate the blood, cerebrospinal fluid barrier and achieve effective fungicidal concentrations. These newer azoles may change the outlook of this fatal condition. We report here a patient with cerebral aspergillosis who was successfully treated with voriconazole.

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Year:  2006        PMID: 16630219     DOI: 10.1111/j.1365-2257.2006.00737.x

Source DB:  PubMed          Journal:  Clin Lab Haematol        ISSN: 0141-9854


  3 in total

1.  The efficacy of voriconazole in the treatment of 192 fungal central nervous system infections: a retrospective analysis.

Authors:  S Schwartz; A Reisman; P F Troke
Journal:  Infection       Date:  2011-04-22       Impact factor: 3.553

Review 2.  A Systematic Review to Assess the Relationship between Disseminated Cerebral Aspergillosis, Leukemias and Lymphomas, and Their Respective Therapeutics.

Authors:  Brianne N Sullivan; Mia A Baggett; Samantha S O'Connell; Keith M Pickett; Chad Steele
Journal:  J Fungi (Basel)       Date:  2022-07-11

Review 3.  Aspergillosis of central nervous system in patients with leukemia and stem cell transplantation: a systematic review of case reports.

Authors:  Aref Shariati; Mojtaba Didehdar; Shahin Rajaeih; Alireza Moradabadi; Mohammad Ghorbani; Vahid Falahati; Zahra Chegini
Journal:  Ann Clin Microbiol Antimicrob       Date:  2021-06-15       Impact factor: 3.944

  3 in total

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