Literature DB >> 16629624

Nogo in the injured spinal cord.

Rüdiger Schweigreiter1, Christine E Bandtlow.   

Abstract

Myelin of the adult mammalian central nervous system (CNS) has been attributed to suppress structural plasticity and to impede regenerating nerve fibers. Nogo-A is possibly the best characterized of a variety of neurite growth inhibitors present in CNS myelin. Neutralizing its activity results in improved axon regrowth and functional recovery in experimental CNS lesion models of adult rodents and primates. While Nogo-A has become a major target for therapeutic intervention to promote axon regeneration in the CNS, it is realized that such an approach will likely have to be combined with other therapeutic strategies to maximize functional recovery after spinal cord injury (SCI).

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16629624     DOI： 10.1089/neu.2006.23.384

Source DB:  PubMed          Journal:  J Neurotrauma        ISSN： 0897-7151            Impact factor:   5.269


  10 in total

1.  Nogo/RTN4 isoforms and RTN3 expression protect SH-SY5Y cells against multiple death insults.

Authors:  Felicia Yu Hsuan Teng; Bor Luen Tang
Journal:  Mol Cell Biochem       Date:  2013-08-18       Impact factor: 3.396

Review 2.  Endocytosis and endosomes at the crossroads of regulating trafficking of axon outgrowth-modifying receptors.

Authors:  Bettina Winckler; Chan Choo Yap
Journal:  Traffic       Date:  2011-05-23       Impact factor: 6.215

3.  Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration.

Authors:  Jeremy H Herskowitz; Nicholas T Seyfried; Duc M Duong; Qiangwei Xia; Howard D Rees; Marla Gearing; Junmin Peng; James J Lah; Allan I Levey
Journal:  J Proteome Res       Date:  2010-10-22       Impact factor: 4.466

Review 4.  Small-molecule-induced Rho-inhibition: NSAIDs after spinal cord injury.

Authors:  M A Kopp; T Liebscher; A Niedeggen; S Laufer; B Brommer; G J Jungehulsing; S M Strittmatter; U Dirnagl; J M Schwab
Journal:  Cell Tissue Res       Date:  2012-02-21       Impact factor: 5.249

5.  Stem cells for spinal cord regeneration: Current status.

Authors:  Zain A Sobani; Syed A Quadri; S Ather Enam
Journal:  Surg Neurol Int       Date:  2010-12-25

6.  Nogo-A couples with Apg-1 through interaction and co-ordinate expression under hypoxic and oxidative stress.

Authors:  Florian Kern; Ruslan I Stanika; Bettina Sarg; Martin Offterdinger; Daniel Hess; Gerald J Obermair; Herbert Lindner; Christine E Bandtlow; Ludger Hengst; Rüdiger Schweigreiter
Journal:  Biochem J       Date:  2013-10-15       Impact factor: 3.857

7.  Nogo-A expression dynamically varies after spinal cord injury.

Authors:  Jian-Wei Wang; Jun-Feng Yang; Yong Ma; Zhen Hua; Yang Guo; Xiao-Lin Gu; Ya-Feng Zhang
Journal:  Neural Regen Res       Date:  2015-02       Impact factor: 5.135

Review 8.  Minocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury.

Authors:  Robert B Shultz; Yinghui Zhong
Journal:  Neural Regen Res       Date:  2017-05       Impact factor: 5.135

9.  Schwann Cell Expressed Nogo-B Modulates Axonal Branching of Adult Sensory Neurons Through the Nogo-B Receptor NgBR.

Authors:  Christoph Eckharter; Nina Junker; Lilli Winter; Irmgard Fischer; Barbara Fogli; Steffen Kistner; Kristian Pfaller; Binhai Zheng; Gerhard Wiche; Lars Klimaschewski; Rüdiger Schweigreiter
Journal:  Front Cell Neurosci       Date:  2015-11-23       Impact factor: 5.505

Review 10.  Hydrogel-based local drug delivery strategies for spinal cord repair.

Authors:  Robert B Shultz; Yinghui Zhong
Journal:  Neural Regen Res       Date:  2021-02       Impact factor: 5.135
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.