BACKGROUND: Candida albicans continues to be the fungus most often causing disease in surgical patients, but with the treatment of an increasing number of critically ill and immunosuppressed patients, other candidal and non-candidal fungal pathogens are becoming more common. METHODS: Review of current practice and guidelines. RESULTS: The presentation and management of non-C. albicans fungal infections differs depending on the genus and species. The availability of newer anti-fungal agents has in many cases improved outcomes or decreased toxicities associated with these diseases. CONCLUSIONS: Although such infections are still relatively uncommon, a working knowledge of infections with non-C. albicans fungi may be beneficial for surgeons, who are likely to encounter such patients both primarily and in consultation. Prompt recognition and treatment of these diseases should improve outcomes.
BACKGROUND:Candida albicans continues to be the fungus most often causing disease in surgical patients, but with the treatment of an increasing number of critically ill and immunosuppressed patients, other candidal and non-candidal fungal pathogens are becoming more common. METHODS: Review of current practice and guidelines. RESULTS: The presentation and management of non-C. albicansfungal infections differs depending on the genus and species. The availability of newer anti-fungal agents has in many cases improved outcomes or decreased toxicities associated with these diseases. CONCLUSIONS: Although such infections are still relatively uncommon, a working knowledge of infections with non-C. albicans fungi may be beneficial for surgeons, who are likely to encounter such patients both primarily and in consultation. Prompt recognition and treatment of these diseases should improve outcomes.
Authors: Tjasa Hranjec; Laura H Rosenberger; Brian Swenson; Rosemarie Metzger; Tanya R Flohr; Amani D Politano; Lin M Riccio; Kimberley A Popovsky; Robert G Sawyer Journal: Lancet Infect Dis Date: 2012-08-28 Impact factor: 25.071