OBJECTIVE: To correlate prognosis of hypoxic-ischemic white-matter injury with magnetic resonance imaging (MRI). METHODS: In a retrospective review at an urban medical center, three adult and three pediatric patients with predominant white-matter involvement caused by hypoxic- ischemic injury were evaluated over a 15-month period. RESULTS: Five patients with MRI-defined hypoxic-ischemic leukoencephalopathy had a favorable outcome, and one with associated diffusion-weighted abnormality of deep gray structures died. CONCLUSION: The prognosis of hypoxic-ischemic leukoencephalopathy is more favorable than previously reported, and diffusion-weighted imaging abnormality of deep gray structures was associated with a poor outcome.
OBJECTIVE: To correlate prognosis of hypoxic-ischemic white-matter injury with magnetic resonance imaging (MRI). METHODS: In a retrospective review at an urban medical center, three adult and three pediatric patients with predominant white-matter involvement caused by hypoxic- ischemic injury were evaluated over a 15-month period. RESULTS: Five patients with MRI-defined hypoxic-ischemic leukoencephalopathy had a favorable outcome, and one with associated diffusion-weighted abnormality of deep gray structures died. CONCLUSION: The prognosis of hypoxic-ischemic leukoencephalopathy is more favorable than previously reported, and diffusion-weighted imaging abnormality of deep gray structures was associated with a poor outcome.
Authors: N Pavese; A Napolitano; G De Iaco; R Canapicchi; P L Collavoli; C Lucetti; G Gambaccini; U Bonuccelli Journal: Ital J Neurol Sci Date: 1999-06