Literature DB >> 16627730

Pharmacology. Hitting the hot spots of cell signaling cascades.

John Joseph Grubb Tesmer1.   

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Year:  2006        PMID: 16627730     DOI: 10.1126/science.1126903

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


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  13 in total

1.  A kinetic model for calcium dynamics in RAW 264.7 cells: 2. Knockdown response and long-term response.

Authors:  Mano Ram Maurya; Shankar Subramaniam
Journal:  Biophys J       Date:  2007-05-04       Impact factor: 4.033

Review 2.  State-selective binding peptides for heterotrimeric G-protein subunits: novel tools for investigating G-protein signaling dynamics.

Authors:  Christopher A Johnston; Francis S Willard; J Kevin Ramer; Rainer Blaesius; C Natalia Roques; David P Siderovski
Journal:  Comb Chem High Throughput Screen       Date:  2008-06       Impact factor: 1.339

3.  Inhibition of heterotrimeric G protein signaling by a small molecule acting on Galpha subunit.

Authors:  Mohammed Akli Ayoub; Marjorie Damian; Christian Gespach; Eric Ferrandis; Olivier Lavergne; Olivier De Wever; Jean-Louis Banères; Jean-Philippe Pin; Grégoire Pierre Prévost
Journal:  J Biol Chem       Date:  2009-07-31       Impact factor: 5.157

4.  Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex.

Authors:  Alexander Shavkunov; Neli Panova; Anesh Prasai; Ron Veselenak; Nigel Bourne; Svetla Stoilova-McPhie; Fernanda Laezza
Journal:  Assay Drug Dev Technol       Date:  2012-02-24       Impact factor: 1.738

5.  Expanding the conformational selection paradigm in protein-ligand docking.

Authors:  Guray Kuzu; Ozlem Keskin; Attila Gursoy; Ruth Nussinov
Journal:  Methods Mol Biol       Date:  2012

6.  Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents.

Authors:  Stephen M Massa; Tao Yang; Youmei Xie; Jian Shi; Mehmet Bilgen; Jeffrey N Joyce; Dean Nehama; Jayakumar Rajadas; Frank M Longo
Journal:  J Clin Invest       Date:  2010-04-19       Impact factor: 14.808

7.  Protein-Protein Interactions as New Targets for Ion Channel Drug Discovery.

Authors:  Svetla Stoilova-McPhie; Syed Ali; Fernanda Laezza
Journal:  Austin J Pharmacol Ther       Date:  2013-12-31

8.  Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interaction.

Authors:  Anton Simeonov; Adam Yasgar; Ajit Jadhav; G L Lokesh; Carleen Klumpp; Sam Michael; Christopher P Austin; Amarnath Natarajan; James Inglese
Journal:  Anal Biochem       Date:  2007-12-05       Impact factor: 3.365

9.  Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior.

Authors:  Noelle C Anastasio; Scott R Gilbertson; Marcy J Bubar; Anton Agarkov; Sonja J Stutz; Yowjiun Jeng; Nicole M Bremer; Thressa D Smith; Robert G Fox; Sarah E Swinford; Patricia K Seitz; Marc N Charendoff; John W Craft; Fernanda M Laezza; Cheryl S Watson; James M Briggs; Kathryn A Cunningham
Journal:  J Neurosci       Date:  2013-01-23       Impact factor: 6.167

Review 10.  In silico pharmacology for drug discovery: applications to targets and beyond.

Authors:  S Ekins; J Mestres; B Testa
Journal:  Br J Pharmacol       Date:  2007-06-04       Impact factor: 8.739

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